CompletedNCT02518880DYMCOUpdated Aug 10, 2015

Dynamics of Stroke Volume and Cardiac Output During Parabolic Flight, and Its Relationship to Intravascular Volume

An interventional study of Parabolic flight and plasma volume measurements in Healthy Volunteers, sponsored by University Hospital, Caen. Completed at 1 site in France. Open to participants aged 18 Years to 55 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2015-08-10.

Sponsored by University Hospital, Caen · Not applicable, Interventional, and Basic science

Phase: Not applicable
Study type: Interventional
Enrollment: 18
Allocation: Not applicable
Ages: 18 Years to 55 Years
Sex: All

Study summary

To understand the cardiovascular reactions of the human body to changing conditions of gravity is an important aim of space science. In this context, cardiac output (CO) is a key value to estimate the human cardiovascular system.

The main objective of this experiment is to determine the effects of parabolic flight on intravascular volume, and how these changes modulate the complex haemodynamics induced by the parabolas.

Conditions studied

Healthy Volunteers

In context

Lead sponsor

University Hospital, Caen is the lead sponsor of 505 studies on the registry; 80 are open to participants now.

Counted across the registry records on this site, refreshed daily.

Who can participate

Ages eligible: 18 Years to 55 Years
Sexes eligible: All
Accepts healthy volunteers: Yes

Inclusion criteria

healthy volunteers (men or women),
aged from 18 to 55,
affiliated to a Social Security system,
who accept to take part in the study,
who have given their written stated consent,
who already participated in parabolic flights (even in the same campaign)
All subjects will pass a medical examination similar to a standard aviation medical examination for private pilot aptitude. There will be no additional test performed for subject selection

Exclusion criteria

Exclusion Criteria:

person who took part in a previous biomedical research protocol, of which exclusion period is not terminated,
pregnant women

Study design

Phase: Not applicable
Primary purpose: Basic science
Allocation: Not applicable
Intervention model: Single group
Masking: None (open label)
Enrollment: 18 participants (actual)

Study arms

Other
Plasma volume measurements
Other: Parabolic flight · Other: plasma volume measurements

Interventions

OtherParabolic flight
Otherplasma volume measurements

What researchers measure

Primary outcomes

haemoglobin concentration
Time frame: baseline

Study locations

1 site

Umr Ucbn/Inserm U1075 Comete
Caen CEDEX, Basse-Normandie 14032, France

Updates

Tracking since Sep 25, 2026

No changes since tracking began. The registry record was last updated on Aug 10, 2015, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗

Registry details

Key details

Study ID: NCT02518880
Lead sponsor: University Hospital, Caen
Responsible party: Sponsor
First posted: Aug 10, 2015
Start date: Mar 2010
Primary completion: Feb 2012
Last update: Aug 10, 2015

Oversight

Data monitoring committee: No

View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Aug 2015. You cannot join it, but the record below documents what was studied.

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Discussion

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