Choroideremia clinical trials
The registry lists 34 studies for Choroideremia across more than 10 countries. 7 are recruiting or about to start. 16 of them are mainly about Choroideremia (how this is decided). Per ClinicalTrials.gov, last updated 2026-07-06.
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Status
Who runs them
Biogen (4) · University of Alberta (2) · 4D Molecular Therapeutics (2) · NightstaRx Ltd, a Biogen Company (2) · Center for Eye Research Australia (2) · Science Corporation (2) · University of Oxford (2) · Ray Therapeutics, Inc. (2)
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 3
- Dec 2026Longitudinal Study of a Bionic Eye · Center for Eye Research Australia
- Dec 2026HYPER MIND - Hyperoxia Effects on Cerebral Hemodynamics · Erasme University Hospital
- May 2027Dose Escalation Study of Intravitreal 4D-110 in Patients With Choroideremia · 4D Molecular Therapeutics
Who these studies take
Of the 6 Choroideremia studies recruiting now, 6 (100%) set no upper age limit and 0 (0%) stop at 75 or younger. 2 (33%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 3 (50%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 2 (33%) | 2 (33%) |
| 18 | 5 (83%) | 5 (83%) |
| 30 | 5 (83%) | 5 (83%) |
| 40 | 5 (83%) | 5 (83%) |
| 50 | 6 (100%) | 6 (100%) |
| 65 | 6 (100%) | 6 (100%) |
| 75 | 6 (100%) | 6 (100%) |
| 85 | 6 (100%) | 6 (100%) |
Across all 34 studies, recruiting or not: 3% stop at 75 or younger and 3% at 65; 18% take children; 0% are for women only and 47% for men only; 18% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
Studies
Recruiting first, then most recently updated. Showing 34 of 34. search them.
- Inherited Retinal Degenerative Disease RegistryRecruitingNCT024359401 country
- High Resolution Retinal ImagingRecruitingNCT018663711 country
- HYPER MIND - Hyperoxia Effects on Cerebral HemodynamicsRecruitingNCT07377162Not applicable1 country
- Observational Study to Assess Endpoint Operational Feasibility & Measurement Properties in Patients with Retinal DegenerationRecruitingNCT063752391 country
- Longitudinal Study of a Bionic EyeEnrolling by invitationNCT051580491 country
- Effects of Aerobic Exercise on the Cerebral Arterial System, Cognitive, and Motor Function in Post-stroke Patients.RecruitingNCT05706168Not applicable1 country
- Structural and Functional Characterization of Rare Ocular DiseasesRecruitingNCT052580321 country
- Long-term Safety and Efficacy Follow-up of BIIB111 for the Treatment of Choroideremia and BIIB112 for the Treatment of X-Linked Retinitis PigmentosaCompletedNCT03584165Phase 39 countries
- A Phase I/II Dose-escalating Study of the Safety, Tolerability and Efficacy of KIO-301 Administered Intravitreally to Patients With Retinitis Pigmentosa and Choroideremia (ABACUS)CompletedNCT05282953Phase 1/21 country
- Study to Evaluate Safety of RTx-015 Injection in Retinitis Pigmentosa or Choroideremia Patients (ENVISION)Active, not recruitingNCT06460844Phase 11 country
- Dose Escalation Study of Intravitreal 4D-110 in Patients With ChoroideremiaActive, not recruitingNCT04483440Phase 11 country
- A Safety Study of Retinal Gene Therapy for Choroideremia With Administration of BIIB111CompletedNCT03507686Phase 23 countries
- Safety and Dose-escalation Study of AAV2-hCHM in Participants With CHM (Choroideremia) Gene MutationsCompletedNCT02341807Phase 1/21 country
- Efficacy and Safety of BIIB111 for the Treatment of ChoroideremiaCompletedNCT03496012Phase 38 countries
- The Dark-Adapted Retinal Function Response in Choroideremia (DARC) StudyWithdrawnNCT05045703Not applicable1 country
- Natural History of the Progression of Choroideremia StudyCompletedNCT033595519 countries
- An Open Label Clinical Trial of Retinal Gene Therapy for ChoroideremiaCompletedNCT02077361Phase 1/21 country
- "Natural History" Study of ChoroideremiaTerminatedNCT029943682 countries
- A Study to Assess Choroideremia (CHM) Health OutcomesCompletedNCT047507851 country
- Natural Disease Progression in Participants With ChoroideremiaCompletedNCT047952061 country
- Study of a Suprachoroidal Retinal ProsthesisCompletedNCT03406416Not applicable1 country
- REP1 Gene Replacement Therapy for ChoroideremiaCompletedNCT02407678Phase 21 country
- THOR - Tübingen Choroideremia Gene Therapy TrialCompletedNCT02671539Phase 21 country
- Invasive Versus Non Invasive Measurement of Intracranial Pressure in Brain Injury Trial (IMPRESSIT)Status unknownNCT023229701 country
- Choroideremia Gene Therapy Clinical TrialCompletedNCT02553135Phase 21 country
- Compensation for Blindness With the Intelligent Retinal Implant System (IRIS V2) in Patients With Retinal DystrophyCompletedNCT02670980Not applicable5 countries
- Impact on Daily Life of Patients Using the Subretinal Implant RETINA IMPLANT Alpha AMSTerminatedNCT03561922Not applicable1 country
- Gene Therapy for Blindness Caused by ChoroideremiaCompletedNCT01461213Phase 1/21 country
- Restoring Vision With the Intelligent Retinal Implant System (IRIS V1)in Patients With Retinal DystrophyCompletedNCT01864486Not applicable3 countries
- Pilot Study of a Suprachoroidal Retinal ProsthesisCompletedNCT01603576Not applicable1 country
- Cerebral Blood Flow During CPB During Cardiac Surgery and the Presence of Post op DeliriumCompletedNCT020843941 country
- Cerebral Hemodynamics With rTMS in Alcohol DependenceCompletedNCT02446067Not applicable1 country
- The Short-term Effects of Simvastatin on the Vision of Males Affected by ChoroideremiaTerminatedNCT01654562Phase 1/21 country
- IRIS PILOT - Extended Pilot Study With a Retinal Implant SystemStatus unknownNCT00427180Not applicable