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CompletedNCT02393430Updated Mar 19, 2015

Clinical Effect of Rebamipide on Chronic Gastritis

A Phase 4 interventional study of Rebamipide and optimization of life style in Gastritis, sponsored by BangMao Wang. Completed. Per ClinicalTrials.gov, last updated 2015-03-19.

Sponsored by BangMao Wang · Phase 4, Interventional, and Treatment

Phase
Phase 4
Study type
Interventional
Enrollment
180
Allocation
Randomized
Sex
All
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Study summary

To investigate the clinical effect of rebamipide in chronic gastritis patients. Patients with chronic gastritis were randomly divided into the experimental group and the control group. The experimental group were treated with rebamipide 0.1g tid and optimization of life style, and the control group were only optimized their life style for 26 weeks. Upper gastrointestinal endoscopy was performed in all patients to evaluate the severity of gastritis by modified Lanza score (MLS) and the histology by the updated Sydney system before and after treatment.

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Conditions studied

  • Gastritis

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03

In context

Gastritis

196 studies on the registry are indexed under Gastritis; 42 are open to participants now.

This study's enrollment of 180 is close to the median of 200 across 113 interventional studies indexed under Gastritis.

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Lead sponsor

This is the only study on the registry with BangMao Wang as lead sponsor.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
Child (0–17), Adult (18–64), Older adult (65+)
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • With the symptoms as follow: epigastric pain, abdominal discomfort, abdominal distention, poor appetite, nausea, vomiting and so on
  • diagnosed as chronic gastritis with endoscopic and pathological methods
  • agree to join in this clinical trail

Exclusion criteria

Exclusion Criteria:

-

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Study design

Phase
Phase 4
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
180 participants (actual)

Study arms

  • Experimental
    experimental

    The experimental group were treated with rebamipide 0.1g tid and optimization of life style.

    Drug: Rebamipide · Behavioral: optimization of life style

  • Placebo comparator
    control

    The control group were only optimized their life style.

    Behavioral: optimization of life style

Interventions

  • DrugRebamipide

    Rebamipide is a

    Also known as: Mucosta

  • Behavioraloptimization of life style
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What researchers measure

Primary outcomes

  1. modified Lanza score

    Time frame: 26 weeks

  2. visual Analog scale

    to describe the inflamamtory of gastric mucosa pathologically

    Time frame: 26 weeks

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Study locations

No study locations are listed for this record.

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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Mar 19, 2015, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT02393430
Lead sponsor
BangMao Wang
Responsible party
BangMao Wang (Chief of Gastroenterology Department, Tianjin Medical University General Hospital) — Sponsor-investigator
First posted
Mar 19, 2015
Start date
May 2012
Primary completion
Jun 2014
Completion
Jun 2014
Last update
Mar 19, 2015

Study contacts

Wang Bang-mao
study chair · Tianjin meidcal university general hospital,China

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Mar 2015. You cannot join it, but the record below documents what was studied.

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