An interventional study of olfactory workshop and other workshop in Anorexia, sponsored by Fondation Lenval. Completed at 1 site in France. Open to participants aged 11 Years to 18 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2019-02-26.
Sponsored by Fondation Lenval · Not applicable, Interventional, and Health services research
This prospective pilot study will compare adolescents with restrictive anorexia nervosa who participated for 3 months at olfactory workshops, patients who did not, and healthy patients.The groups will be evaluated before the workshops and after three months, with the wanting score after olfactory stimuli and with serum oxytocin level.
The restrictive anorexia nervosa (AN) in adolescents is an eating disorder with decreased desire to eat (wanting) following olfactory stimulation. Oxytocin is an hormone involved in the neuromodulation of eating behavior, but also involved in olfactory perception in schizophrenia patients, and in social cognition in patients with autism. Its plasma level was found low in anorexic patients compared to control subjects.
Because of the similarity in disorders of social cognition between these three diseases, we assume that the desire to eat evoked by olfactory perception varies with the plasma oxytocin levels.
With a prospective pilot study we will compare patients with AN who participated for 3 months at olfactory workshops, AN patients who did not, and healthy patients.
The groups will be evaluated before the workshops and after three months, with the wanting score after olfactory stimuli and with serum oxytocin level.
One application of this study will be the use of ocytocyne nasal spray to increase the eating desire and to allow weight regain
411 studies on the registry are indexed under Anorexia; 67 are open to participants now.
This study's enrollment of 30 is below the median of 41 across 287 interventional studies indexed under Anorexia.
Browse Anorexia studies →Fondation Lenval is the lead sponsor of 60 studies on the registry; 18 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Influence of sensory therapy on the rate of oxytocin
Other: olfactory workshop
Influence of other workshop on the rate of oxytocin
Other: other workshop
Rate of oxytocin of the control group
Other: No intervention
olfactory workshop
other workshop: discussion group, dance and body Expression
control group
Score "Wanting" to olfactory stimuli
Time frame: at 3 months
Oxytocin serum level
Time frame: at 3 months
Body mass index
Time frame: at 3 months
Scores to clinical scales
Time frame: at 3 months
Scores to hedonicity scale
Time frame: at 3 months
Scores to "liking"-"wanting" tests
Time frame: at 3 months
This study is completed, as verified in Jul 2018. You cannot join it, but the record below documents what was studied.
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Fondation Lenval