An observational study in Quality of Life and Stigmatization, sponsored by University Children's Hospital, Zurich. Recruiting at 1 site in Switzerland. Open to participants aged 9 Months to 16 Years. Per ClinicalTrials.gov, last updated 2026-03-04.
Sponsored by University Children's Hospital, Zurich · Observational
Congenital melanocytic nevi (CMN) are a quite common congenital disorder. Over years, surgical excision was proposed to the patients because transformation into a malignant skin tumor (melanoma) was feared. Recent data proof that the risk for malignancy was overestimated. Nowadays still a lot of patients express their wish for surgical removal out of aesthetic reasons and psychological impacts. Many patients and families experience stigmatization because of the nevus. To proof a medical indication for surgical removal the investigators want to evaluate the quality of life and stigmatization before and after nevus surgery.
All children with CMN that will have their nevus removed in our surgical department will be asked to participate. The investigators will send a package of questionnaires to evaluate quality of life and stigmatization before nevus surgery. One year after surgical therapy is finished (sometimes more then one session is necessary), the scar will be clinically evaluated and also another questionnaire package will be sent to evaluate the same parameters again. All parameters are checked for the patients and the families as well. Therefore self and proxy reports of the parents are asked. Moreover, for the patients this is done with interviews in case they are older than 7 years.
47 studies on the registry are indexed under Nevus; 9 are open to participants now.
This study's planned enrollment of 100 is below the median of 145 across 28 observational studies indexed under Nevus.
Browse Nevus studies →University Children's Hospital, Zurich is the lead sponsor of 95 studies on the registry; 23 are open to participants now.
Compared within Nevus, this study's primary condition as ClinicalTrials.gg classifies it; the registry's first condition term is Stereotyping. The counts are of registry records indexed under each term, refreshed daily. How we classify →
All patients with CMN of at least 2 square centimeter (projected adult size) that are scheduled for surgical removal of the CMN at our tertiary center for pediatric surgery.
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Exclusion Criteria:
Change of Quality of Life of affected children before and after surgery
Quality of life with the CMN and in comparison with the scar after nevus excision is measured using validated age-related questionnaires respectively one-to one interviews
Time frame: Before surgery, up to 90 days after screening and one year after surgery
Change of experiences of stigmatization before and after surgery
Stigmatization experiences of patients and parents before CMN surgery in comparison with after nevus excision are measured using standardized and validated questionnaires
Time frame: Before surgery, up to 90 days after screening and one year after surgery
Satisfaction with the treatment
Satisfaction with the treatment is evaluated one year after the last surgical step using open questions with rating scales
Time frame: One year after surgery
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University Children's Hospital, Zurich