An observational study in Atrial Fibrillation and Atrial Flutter, sponsored by University of Limerick. Completed at 1 site in Ireland. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2015-08-13.
Sponsored by University of Limerick · Observational
The purpose of this study is to determine if there is a rise in serum high sensitivity troponin T (a marker for heart muscle injury) following a direct current cardioversion (shock therapy) used for patients with atrial fibrillation. This will help us determine if direct current cardioversion results in damage to the heart muscles in a sufficient amount to cause a rise in high sensitivity troponin T.
High sensitivity Troponin T is a relatively new biomarker that is highly sensitive and specific for myocardial injury. Its widespread use has helped in the determination and investigation for myocardial ischemia in patients. Previous studies have shown a rise in creatine kinase (CK) and the more specific creatine kinase-MB isoenzyme (CKMB) after DC cardioversion. Studies on the earlier generation troponin T found that the levels don't rise or rise only minimally after DC cardioversion. The high sensitivity troponin T has never been studied in the setting of DC cardioversion.
3,870 studies on the registry are indexed under Atrial Fibrillation; 924 are open to participants now.
This study's enrollment of 101 is below the median of 300 across 1,363 observational studies indexed under Atrial Fibrillation.
Browse Atrial Fibrillation studies →University of Limerick is the lead sponsor of 56 studies on the registry; 9 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Patients with atrial fibrillation/flutter who attend the Coronary Care Unit of the University Hospital Limerick for a pre-organised appointment for direct current external cardioversion will be requested to participate in the study
Exclusion Criteria:
Patients undergoing DC cardioversion
High Sensitivity Troponin T levels pre and 6 hours post cardioversion
Time frame: 1 year
Creatine Kinase levels pre and 6 hours post cardioversion
Time frame: 1 year
B-type Natriuretic Peptide (BNP) levels pre and 6 hours post cardioversion
Time frame: 1 year
Neutrophil Gelatinase-associated Lipocalin (NGAL) levels pre and 6 hours post cardioversion
Time frame: 1 year
This study is completed, as verified in Aug 2015. You cannot join it, but the record below documents what was studied.
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University of Limerick