An interventional study of Internet-delivered Cognitive Behavior Therapy in Obsessive-Compulsive Disorder, sponsored by Karolinska Institutet. Completed at 1 site in Sweden. Open to participants aged 12 Years to 17 Years. Per ClinicalTrials.gov, last updated 2016-12-22.
Sponsored by Karolinska Institutet · Not applicable, Interventional, and Treatment
The effect of Internet-delivered Cognitive Behavior Therapy (ICBT) on adolescents (12 to 17 years) with Obsessive-Compulsive Disorder is studied. Participants are randomized to either ICBT or a no-treatment condition. We expect ICBT to be superior over the no-treatment condition.
The primary objective of this study is to test the efficacy of Internet-delivered cognitive behavior therapy (ICBT) for adolescents (12 - 17 years) with OCD. We aim to conduct a randomized controlled study with N = 66 participants. Participants will be randomly assigned to ICBT or a wait list condition, either lasting 12 weeks. The primary outcome measure is the Children's Yale-Brown Obsessive Compulsive Scale (CY-BOCS). Study participants will be followed up 3 and 12 months after treatment. ICBT is expected to yield significantly better symptom reduction than the wait list condition.
367 studies on the registry are indexed under Compulsive Personality Disorder; 67 are open to participants now.
This study's enrollment of 67 is above the median of 37 across 306 interventional studies indexed under Compulsive Personality Disorder.
Browse Compulsive Personality Disorder studies →Karolinska Institutet is the lead sponsor of 1,113 studies on the registry; 267 are open to participants now.
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Exclusion Criteria:
Participants will receive 12 weeks of internet-delivered cognitive behavior therapy with psychologist support.
Behavioral: Internet-delivered Cognitive Behavior Therapy
Participants will receive no treatment for 12 weeks. After that period participants will receive Internet-delivered Cognitive Behavior Therapy.
The treatment consists of standard cognitive behavior therapy for obsessive-compulsive disorder and is delivered via an internet plattform and regular therapist contact several times per week via email and telephone. The treatment is 12 weeks.
Children's Yale Brown Obsessive Compulsive Scale, CY-BOCS
Change from Baseline of obsessions and compulsions after 12 weeks and at 3- and 12 months after treatment
Time frame: Baseline, 12 weeks after treatment starts, 3 and 12 months after treatment has ended
Clinical Global Impression - Severity, CGI-S
Time frame: Baseline, 12 weeks after treatment starts, 3 and 12 months after treatment has ended
Clinical Global Impression - Improvement, CGI-I
Time frame: Baseline, 12 weeks after treatment starts, 3 and 12 months after treatment has ended
Parent Adherence EX/RP Scale, PEAS
Time frame: Baseline, 6 and 12 weeks after treatment starts
Children's Obsessional Compulsive Inventory Revised, (CHOCI-R, Shafran et al., 2003)
Time frame: Baseline, 12 weeks after treatment starts, 3 and 12 months after treatment has ended
Education, Work and Social Adjustment Scale - child and parent version (EWSAS)
Time frame: Baseline, 12 weeks after treatment starts, 3 and 12 months after treatment has ended
Spence Child Anxiety Scale - Child and Parent version (SCAS-C/P, Spence, 1998
Time frame: Baseline, 12 weeks after treatment starts, 3 and 12 months after treatment has ended
Child Depression Inventory - Short version (CDI-S, Kovacs, 1985)
Time frame: Baseline, 12 weeks after treatment starts, 3 and 12 months after treatment has ended
Family Accommodation Scale, Parent-Report (FAS-PR, Flessner et al., 2009)
Time frame: Baseline, 12 weeks after treatment starts, 3 and 12 months after treatment has ended
Technology acceptance scale
Time frame: Baseline, 6 and 12 weeks after treatment starts,
Trimbos/iMTA questionnaire for Costs associated with Psychiatric Illness - Child version (TiC-P)
Time frame: Baseline, 12 weeks after treatment starts, 3 and 12 months after treatment has ended
EQ-5D - quality of life
Time frame: Baseline, 12 weeks after treatment starts, 3 and 12 months after treatment has ended
Measurement of homework adherence
Time frame: Baseline, daily measurements until 12 weeks after baseline
Number of Participants with Adverse Events
Time frame: 12 weeks after baseline
DNA samples (from blood and/or saliva)
Time frame: Baseline
Plan to share: Undecided
This study is completed, as verified in Dec 2016. You cannot join it, but the record below documents what was studied.
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Compulsive Personality Disorder→
Karolinska Institutet