An observational study in Bladder Cancer, sponsored by Huazhong University of Science and Technology. Status unknown at 1 site in China. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2014-08-04.
Sponsored by Huazhong University of Science and Technology · Observational
The aim of this study is to compare the health-related quality of life (HRQoL) between patients underwent conduit diversion and orthotopic neobladder after radical cystectomy. The investigators plan to use validated HRQoL questionnaires to learn about how the different urinary diversion operations affect the HRQoL of people living with bladder cancer. The findings from this study may help doctors and patients choosing the proper operation type.
1,616 studies on the registry are indexed under Urinary Bladder Neoplasms; 421 are open to participants now.
This study's planned enrollment of 300 is above the median of 180 across 374 observational studies indexed under Urinary Bladder Neoplasms.
Browse Urinary Bladder Neoplasms studies →Huazhong University of Science and Technology is the lead sponsor of 241 studies on the registry; 60 are open to participants now.
Counted across the registry records on this site, refreshed daily.
All eligible patients in Wuhan Union Hospital, Huazhong University of Science and Technology.
Exclusion Criteria:
new patients with bladder cancer scheduled for radical cystectomy and subsequent conduit diversion
Behavioral: validated health-related quality of life questionnaires
new patients with bladder cancer scheduled for radical cystectomy and subsequent orthotopic neobladder
Behavioral: validated health-related quality of life questionnaires
All eligible patients who agree to participate will be asked to fulfill three different validated health-related quality of life questionnaires (EORTC-QLQ-C30/BLM, FACT-BL and BCI) prior to surgery and at 3, 6, 12, 18 months postoperatively.
Change from baseline in HRQoL of bladder cancer patients with different types of urinary diversions
Time frame: Preoperative baseline and 3, 6, 12, 18 months postoperatively
Score differences between the two groups of patients in the relevant domains from three various validated tools of HRQoL
The aim is to compare three various validated tools of HRQoL to study their relative contributions in accounting for variance in prediction of patient HRQoL. The three validated tools of HRQoL are EORTC-QLQ-C30/BLM (The European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire/bladder cancer module), FACT-BL (Functional Assessment of Cancer Therapy-Bladder cancer) and BCI (Bladder Cancer Index). The two groups are conduit diversion group and orthotopic neobladder group.
Time frame: Preoperative baseline and 3, 6, 12, 18 months postoperatively
Score changes of each patient group during the follow-up
Longitudinally learn about the changes of each individual patient HRQoL after urinary diversion and compare the changes of two groups, i.e. conduit diversion group and orthotopic neobladder group.
Time frame: Preoperative baseline and 3, 6, 12, 18 months postoperatively
Objective examination outcomes
Supplement the assessment by interviewing the patients with some lab and image examinations, such as renal function tests, liver function tests, urine culture, urine cytology, chest radiography, ultrasound of kidney, ureter and bladder (KUB) etc.
Time frame: Preoperative baseline and 3, 6, 12, 18 months postoperatively
This study is status unknown, as verified in Aug 2014. You cannot join it, but the record below documents what was studied.
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Huazhong University of Science and Technology