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Status unknownNCT02108340Updated Feb 14, 2017

Comparative Study of Microwave Radiometry and Ultrasonography for the Diagnosis of Acute Appendicitis

An interventional study of Microwave radiometry in Appendicitis, sponsored by Hippocration General Hospital. Status unknown at 1 site in Greece. Per ClinicalTrials.gov, last updated 2017-02-14.

Sponsored by Hippocration General Hospital · Not applicable, Interventional, and Diagnostic

The sponsor has not verified this record recently (last verified Feb 2017), so the status shown — last known as Recruiting — may be out of date.
Phase
Not applicable
Study type
Interventional
Enrollment
40
Allocation
Not applicable
Sex
All
01

Study summary

This study will evaluate the use of microwave radiometry in a population of patients diagnosed with acute appendicitis and treated with appendectomy. The main purpose of the study is to report the results of microwave radiometry as a diagnostic tool in acute appendicitis and compare those results with the commonly used ultrasonography.

Read the detailed description

Patients diagnosed with acute appendicitis from the emergency department of Hippocration General Hospital and treated with appendectomy will be evaluated with microwave radiometry for changes in the temperature of the appendix before its removal.

Subsequently, the results of microwave radiometry for the patients confirmed by the histopathology report to have acute inflammation of the appendix, will be compared with those of the ultrasonography used for the diagnosis of acute appendicitis.

02

Conditions studied

  • Appendicitis

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Keywords

  • Appendicitis
  • Diagnosis
  • Microwave radiometry
  • Ultrasonography
03

In context

Appendicitis

412 studies on the registry are indexed under Appendicitis; 62 are open to participants now.

This study's planned enrollment of 40 is below the median of 111 across 246 interventional studies indexed under Appendicitis.

Browse Appendicitis studies →

Lead sponsor

Hippocration General Hospital is the lead sponsor of 27 studies on the registry; 6 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
Child (0–17), Adult (18–64), Older adult (65+)
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • Clinical diagnosis of appendicitis
  • Surgical removal of appendix
  • Pathological confirmation of appendicitis

Exclusion criteria

Exclusion Criteria:

-

05

Study design

Phase
Not applicable
Primary purpose
Diagnostic
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrollment
40 participants (estimated)

Study arms

  • Experimental
    Microwave radiometry

    Patients diagnosed with acute appendicitis will undergo a measurement of the temperature of the appendix with the use of microwave radiometry in a room temperature of 20 -24 degrees celsius.

    Procedure: Microwave radiometry

Interventions

  • ProcedureMicrowave radiometry

    Microwave radiometry of the right lower quadrant in a room temperature of 20-24 degrees celsius, in order to record changes in the temperature of the inflamed appendix.

06

What researchers measure

Primary outcomes

  1. Appendix Temperature

    Microwave radiometry will assess the temperature of the appendix for the patients diagnosed with appendicitis before they undergo surgical removal of the appendix.

    Time frame: Baseline

07

Study locations

1 of 1 sites recruiting
  • Hippocration General hospital
    Athens, Attiki 115 27, Greece
    • Konstantinos G. Toutouzas, MD, PhD · Principal investigator
    • Evagelia Stamouli, MD · Principal investigator
    • Konstantinos Stasinos, MD · Sub investigator
    Recruiting
08

References and documents

Publications

  • Toutouzas K, Grassos C, Drakopoulou M, Synetos A, Tsiamis E, Aggeli C, Stathogiannis K, Klettas D, Kavantzas N, Agrogiannis G, Patsouris E, Klonaris C, Liasis N, Tousoulis D, Siores E, Stefanadis C. First in vivo application of microwave radiometry in human carotids: a new noninvasive method for detection of local inflammatory activation. J Am Coll Cardiol. 2012 May 1;59(18):1645-53. doi: 10.1016/j.jacc.2012.01.033. PubMed 22538335 ↗
  • Arunachalam K, Maccarini PF, De Luca V, Bardati F, Snow BW, Stauffer PR. Modeling the detectability of vesicoureteral reflux using microwave radiometry. Phys Med Biol. 2010 Sep 21;55(18):5417-35. doi: 10.1088/0031-9155/55/18/010. Epub 2010 Aug 25. PubMed 20736499 ↗
  • Toutouzas K, Grassos H, Synetos A, Drakopoulou M, Tsiamis E, Moldovan C, Agrogiannis G, Patsouris E, Siores E, Stefanadis C. A new non-invasive method for detection of local inflammation in atherosclerotic plaques: experimental application of microwave radiometry. Atherosclerosis. 2011 Mar;215(1):82-9. doi: 10.1016/j.atherosclerosis.2010.12.019. Epub 2010 Dec 23. No abstract available. PubMed 21256490 ↗
  • Hassan AM, El-Shenawee M. Review of electromagnetic techniques for breast cancer detection. IEEE Rev Biomed Eng. 2011;4:103-18. doi: 10.1109/RBME.2011.2169780. PubMed 22273794 ↗

Individual participant data

Plan to share: Undecided

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Feb 14, 2017, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT02108340
Lead sponsor
Hippocration General Hospital
Responsible party
Konstantinos Toutouzas (Assistant Professor of Surgery, Hippocration General Hospital) — Principal investigator
First posted
Apr 9, 2014
Start date
Sep 2013
Primary completion
Jul 2017 (estimated)
Completion
Aug 2017 (estimated)
Last update
Feb 14, 2017

Study contacts

Konstantinos G. Toutouzas, MD, PhD
Contact
tousur@hotmail.com
00306970801370
Konstantinos G. Toutouzas, MD, PhD
study chair · Hippocration General Hospital
Evagelia Stamouli, MD
principal investigator · Hippocration General Hospital

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in Feb 2017. You cannot join it, but the record below documents what was studied.

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