An interventional study of Direct Referral to physical activity in Multiple Sclerosis, sponsored by McMaster University. Completed at 2 sites in Canada. Open to participants aged 18 Years to 60 Years. Per ClinicalTrials.gov, last updated 2018-05-31.
Sponsored by McMaster University · Not applicable, Interventional, and Other
The proposed project will evaluate two methods of implementation of the new Physical Activity Guidelines (PAGs) for Adults with Multiple Sclerosis (MS) living in two Ontario communities. The investigators will also determine if following the PAGs will improve aspects of fitness, function, quality of life and risk for cardiometabolic disease in this population. The investigators hypothesize that adherence to the PAGs will be higher in people who have been referred directly to a community-based exercise program, and that this greater adherence to physical activity will be associated with greater improvements in fitness, function and quality of life.
This randomized controlled trial will provide important information on how best to implement physical activity recommendations within the community setting; this information will be translated to key stakeholders during the final stages of the project.
3,460 studies on the registry are indexed under Multiple Sclerosis; 661 are open to participants now.
This study's enrollment of 94 is above the median of 50 across 2,342 interventional studies indexed under Multiple Sclerosis.
Browse Multiple Sclerosis studies →McMaster University is the lead sponsor of 720 studies on the registry; 124 are open to participants now.
Of its 6 completed or terminated interventional studies of FDA-regulated products, 2 (33%) have results posted.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
The REF group will be referred to a centre-based community exercise program in their respective community (either the MacWheelers or Revved Up) by a clinical neurologist where they will be prescribed exercise based on the PAGs for adults with MS, and according to their individual capabilities.
Other: Direct Referral to physical activity
The CON group will be provided with a print copy of the PAGs and a link to an online resource for physical activity information.
Participants randomized to the Direct Referral to Physical Activity Arm will be provided with a referral to a physical activity program in their community and will be closely monitored in this program for 16 wks.
Adherence to the Physical Activity Guidelines
Adherence to the physical activity guidelines will be analyzed by having participants fill in a weekly physical activity log that will be sent to them by email.
Time frame: 3 years
Physical Fitness
Peak oxygen uptake, maximum muscle strength, bodyweight
Time frame: At baseline and after the 16 week intervention
Perceived Quality of Life
Multiple Sclerosis Quality of Life (MSQoL) scale
Time frame: At baseline and after the 16 week intervention
Fatigue
Multiple Sclerosis Fatigue Impact Scale (MSFIS)
Time frame: At baseline and after the 16 week intervention
Mobility
25ft walk test
Time frame: At baseline and after the 16 week intervention
Blood markers of cardiovascular disease risk
blood lipid panel, HbA1c, fasting glucose
Time frame: At baseline and after the 16 week intervention
This study is completed, as verified in May 2018. You cannot join it, but the record below documents what was studied.
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