An observational study in Ekg Change Ischemia Lateral, sponsored by Alexandria University. Status unknown at 1 site in Egypt. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2014-01-06.
Sponsored by Alexandria University · Observational
The electrocardiogram (ECG) is a simple and non-invasive bedside diagnostic tool with a well-established role in the diagnosis of (CAD). Many studies have found that the admission of ECG provides important prognostic information in patients admitted with chest pain. For instance, T wave inversion in anterior or inferior location and or ST-segment depression has been associated with high incidence of CAD.
The aim of the work will be directed to study the diagnostic value of electrocardiographic ST-T wave changes in lead aVL in patients with chronic stable angina
The ECG findings vary considerably, depending importantly on four major factors: (1) the duration of the ischemic process (acute versus evolving or chronic) ; (2) its extent (large versus small) ; (3) its topography (anterior versus inferior-posterior and right ventricular) ; (4) the presence of other underlying conditions (e.g. LBBB, WPW or pacemaker pattern) that can mask or alters the classic pattern.
The resting electrocardiogram is normal in approximately half of patients with chronic stable angina pectoris, and even patients with severe CAD may have a normal tracing at rest. A normal resting ECG suggesting a normal LV function and it is unusual finding in a patient with an extensive previous infarction.
The most common electrocardiographic abnormalities in patients with chronic CAD are non specific ST-Twave changes with or without abnormal Q waves. In addition to myocardial ischemia, other conditions that can produce ST-T wave abnormalities include LV hypertrophy or dilation, electrolyte abnormalities, neurogenic effects, and anti-arrhythmic drugs.
In patients with known CAD, however, the occurrence of ST-T wave abnormalities on the resting ECG may correlate with the severity of the underlying heart disease. This association may explain the adverse association of ST-Twave changes with prognosis of these patients. In contrast, a normal resting ECG is more favorable long-term prognostic sign in patients with suspected or definite CAD.
345 studies on the registry are indexed under Angina, Stable; 57 are open to participants now.
This study's planned enrollment of 150 is below the median of 453 across 98 observational studies indexed under Angina, Stable.
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This study will be a prospective observational study conducted on 150 patients admitted at the Alexandria university hospitals or referred from secondary hospitals with documented CAD as proved by non invasive tests (ECG, echocardiography, treadmill exercise, myocardial perfusion imaging or multi-slice CT coronary angiography) requiring invasive coronary angiography.
Exclusion Criteria:
Corelation between ecg finding and coronary angiography finding
the value of t wave and st segment changes in correlation with the cornary angiographic findings
Time frame: 9 months
This study is status unknown, as verified in Jan 2014. You cannot join it, but the record below documents what was studied.
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Alexandria University