CompletedNCT02015624EYESHOTUpdated Feb 3, 2021

EYESHOT (EmploYEd Antithrombotic Therapies in Patients With Acute Coronary Syndromes HOspitalized in iTalian Coronary Care Units)

An observational study in Acute Coronary Syndromes, sponsored by Heart Care Foundation. Completed at 203 sites in Italy. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2021-02-03.

Sponsored by Heart Care Foundation · Observational

Study type: Observational
Model: Other
Time perspective: Cross-sectional
Enrollment: 2,597
Ages: 18 Years and older
Sex: All

Study summary

This register will evaluate the use of different antithrombotic therapies, combinations of different drugs routinely used during any stage of hospital admission, with their timing, dosage and mode of administration, in patients with a diagnosis of Acute Coronary Syndrome in the Italian Coronary Care Unit during a study period of three weeks

Conditions studied

Acute Coronary Syndromes

Browse trials for

Keywords

Acute coronary syndromes
Intensive Care Unit

In context

Acute Coronary Syndrome

1,461 studies on the registry are indexed under Acute Coronary Syndrome; 267 are open to participants now.

This study's enrollment of 2,597 is above the median of 500 across 561 observational studies indexed under Acute Coronary Syndrome.

Browse Acute Coronary Syndrome studies →

Lead sponsor

Heart Care Foundation is the lead sponsor of 22 studies on the registry; 6 are open to participants now.

Counted across the registry records on this site, refreshed daily.

Who can participate

Ages eligible: 18 Years and older
Sexes eligible: All
Accepts healthy volunteers: No
Sampling method: Probability sample

Study population

Patients with a diagnosis of Acute Coronary Syndrome consecutively admitted in the Italian Cardiac Care Unit, located in hospitals with and without cardiac cath lab and cardiac surgery, during a period of 3 weeks

Inclusion criteria

All consecutive patients discharged with a diagnosis of Acute Coronary Syndrome ( Non ST elevation or ST Elevation) undergoing myocardial revascularization or conservative treatment , admitted to the Coronary Care Unit during the observation period established.
Age ≥ 18 years
Signed informed consent

Exclusion criteria

Exclusion criteria:

Patients enrolled in clinical trials of intervention
Diagnosis of Acute Coronary Syndrome caused by confounding comorbidities (eg . Trauma or surgery after non- cardiac )
Patients already enrolled in eyeshot from another center.

Study design

Observational model: Other
Time perspective: Cross-sectional
Enrollment: 2,597 participants (actual)
Patient registry: No

What researchers measure

Primary outcomes

Antithrombotic drugs in patient undergoing percutaneous transluminal coronary angiography, coronary artery bypass graft or no coronary revascularization
Time frame: Participants will be followed for the duration of hospital stay, an expected average period of 7 days

Secondary outcomes

In-hospital ischemic and hemorrhagic events
Time frame: Participants will be followed for the duration of hospital stay, an expected average period of 7 days

Study locations

203 sites

Ospedale San Giovanni Di Dio, S.C. Cardiologia
Agrigento, AG 92100, Italy
Ospedale Barone Lombardo, Cardiologia E Utic
Canicatti', AG 92024, Italy
Ospedali Riuniti, Sod Cardiologia Ospedaliera E Utic
Ancona, AN 60122, Italy
Istituto Scientifico Inrca, Uo Cardiologia/Utic/Telecardiologia
Ancona, AN 60131, Italy
Ospedali Riuniti, U.O. Di Cardiologia
Jesi, AN 60035, Italy
Ospedale Generale Regionale - Po U. Parini - U.O. Cardiologia E Cure Intensive Card.
Aosta, AO 11100, Italy
Ospedale Civile Ss. Filippo E Nicola, U.O. Cardiologia E Utic
Avezzano, AQ 67051, Italy
Ospedale San Donato, U.O. Cardiologia
Arezzo, AR 52100, Italy
Ospedale Miulli, U.O.C. Cardiologia - Utic
Acquaviva Delle Fonti, BA 70021, Italy
Ospedale San Paolo, Cardiologia-Utic
Bari, BA 70123, Italy
Ospedale Consorziale Policlinico, U.O. Cardiologia Universitaria
Bari, BA 70124, Italy
Ospedale Consorziale Policlinico, U.O. Di Cardiologia Ospedaliera
Bari, BA 70124, Italy
Ospedale Di Venere, U.O.C. Di Cardiologia
Carbonara Di Bari, BA 70012, Italy
Azienda Ospedaliera Papa Giovanni Xxiii, U.S.C. Di Cardiologia
Bergamo, BG 24127, Italy
Iob - Policlinico San Pietro, U.O.C. Cardiologia E Utic
Ponte San Pietro, BG 24036, Italy
Ospedale Degli Infermi, Divisione Di Cardiologia
Biella, BI 13900, Italy
Ospedale Santa Maria Del Prato, U.O. Di Cardiologia
Feltre, BL 32032, Italy
Ospedale Di Bentivoglio, U.O. Di Cardiologia
Bentivoglio, BO 40010, Italy
Ospedale Maggiore, U.O. Di Cardiologia
Bologna, BO 40133, Italy
Ospedale Nuovo S. Maria Della Scaletta, Uoc Cardiologia
Imola, BO 40026, Italy
Ospedale Perrino, U.O.C. Di Cardiologia
Brindisi, BR 72100, Italy
Spedali Civili, Cardiologia
Brescia, BS 25123, Italy
Istituto Osped. Fondazione Poliambulanza, Unita' Operativa Di Cardiologia
Brescia, BS 25124, Italy
Ospedale Civile Mellini - Divisione di Cardiologia
Chiari, BS 25032, Italy
Ospedale Civile Di Valle Camonica, Divisione Di Cardiologia
Esine, BS 25040, Italy
Ospedale Generale Regionale
Bolzano, BZ 39100, Italy
Presidio Ospedaliero Ss Trinita', Sc Di Cardiologia
Cagliari, CA 09121, Italy
Ospedale San Giovanni Di Dio, Cattedra E Divisione Di Cardiologia
Cagliari, CA 09124, Italy
Azienda Ospedaliera G. Brotzu
Cagliari, CA 09134, Italy
Ospedale A. Cardarelli, U.O. Cardiologia E Utic
Campobasso, CB 86100, Italy
Ospedale San Timoteo, Uoc Clinica-Intensiva-Vascolare
Termoli, CB 86039, Italy
Clinica Pineta Grande, Unita Terapia Intensiva Coronarica
Castel Volturno, CE 81030, Italy
Ospedale San Giuseppe E Melorio, U.O.C. Cardiologia Utic
Santa Maria Capua Vetere, CE 81055, Italy
Presidio Ospedaliero San Rocco, Emergenze Cardiologiche
Sessa Aurunca, CE 81037, Italy
Ospedale Policlinico Ss. Annunziata, Cardiologia-Utic
Chieti, CH 66100, Italy
Ospedale San Pio Da Pietrelcina, Cardiologia
Vasto, CH 66054, Italy
Az. Ospedaliera Vittorio Emanuele Iii, S.C. Cardiologia - Utic
Gela, CL 93012, Italy
Ospedale Regina Montis Regalis, U.O. Cardiologia-Utic
Mondovi', CN 12084, Italy
Ospedale Maggiore Ss. Annunziata, Sc Cardiologia
Savigliano, CN 12038, Italy
Ospedale Generale Di Zona Valduce, Unita' Operativa Di Cardiologia
Como, CO 22100, Italy
Ospedale Sacra Famiglia Fbf, Unita' Operativa Di Cardiologia
Erba, CO 22036, Italy
Ospedale Moriggia Pelascini, Unita' Operativa Di Cardiologia
Gravedona, CO 22015, Italy
Ospedale S. Anna, U.O.C. Di Cardiologia
San Fermo Della Battaglia, CO 22020, Italy
Ospedale Civile Oglio Po, U.O. Di Cardiologia-Utic
Casalmaggiore, CR 26041, Italy
Istituti Ospitalieri - UO Cardiologia
Cremona, CR 26100, Italy
Ospedale Civile Ferrari, U.O.C. Cardiologia-Utic-Emodinamica
Castrovillari, CS 87012, Italy
Ospedale Santissima Annunziata, Uoc Cardiologia
Cosenza, CS 87100, Italy
Spoke Cetraro-Paola, U.O. Cardiologia E Utic
Paola, CS 87027, Italy
Ospedale Civile N. Giannettasio, U.O. Cardiologia E Utic
Rossano, CS 87067, Italy
P. O. Gravina E Santo Pietro, U.O. Di Cardiologia-Utic
Caltagirone, CT 95041, Italy
P.O. Garibaldi Centro, U.O.C. Cardiologia
Catania, CT 95124, Italy
P.O. Ospedale Ferrarotto-Alessi, U.O. Clinicizzata Di Cardiologia
Catania, CT 95124, Italy
Az Ospedaliera Universitaria Materdomini, U.O. Cardiologia - Campus Universitario
Catanzaro, CZ 88100, Italy
Ospedale Civile Pugliese, Utic-Emodinamica E Card. Interventistica
Catanzaro, CZ 88100, Italy
Ospedale M.Bufalini, U.O. Di Cardiologia-Utic
Cesena, FC 47023, Italy
Ospedale G.B. Morgagni - L. Pierantoni, U.O. Cardiologia
Forli', FC 47100, Italy
Ospedale Ss. Annunziata, U.O. Di Cardiologia
Cento, FE 44042, Italy
Ospedale Del Delta, U.O. Cardiologia
Lagosanto, FE 44023, Italy
Ospedale Civile Giuseppe Tatarella, U.O. Di Cardiologia - Utic
Cerignola, FG 71042, Italy
Ospedali Riuniti, S.C. Di Cardiologia Univ.-Utic
Foggia, FG 71100, Italy
Ospedale casa Sollievo della Sofferenza - Cardiologia - UTIC
San Giovanni Rotondo, FG 71013, Italy
Ospedale Padre Antero Micone, Cardiologia - Utic
Genova, GE 16100, Italy
Irccs San Martino Ist Ricerca Sul Cancro, Unita' Operativa Cardiologia
Genova, GE 16132, Italy
Ospedale Civile San Polo, S.O.C. Cardiologia
Monfalcone, GO 34074, Italy
Ospedale della Misericordia - UO Cardiologia
Grosseto, GR 58100, Italy
Presidio Ospedaliero, U.O. Cardiologia
Sanremo, IM 18038, Italy
Ospedale Civile San Giovanni Di Dio, U.O. Cardiologia
Crotone, KR 88900, Italy
Ospedale Alessandro Manzoni - SC di Cardiologia
Lecco, LC 23900, Italy
Ospedale San Leopoldo Mandic, Cardiologia - Ucc
Merate, LC 23807, Italy
Presidio Ospedaliero F. Ferrari, Cardiologia - Utic
Casarano, LE 73042, Italy
Ospedale San Giuseppe Da Copertino, U.O. Di Cardiologia-Utic
Copertino, LE 73043, Italy
Ospedale Civile Sacro Cuore Di Gesu', Uo Cardiologia Utic
Gallipoli, LE 73014, Italy
Citta' Di Lecce Hospital, U.O. Di Cardiologia
Lecce, LE 73100, Italy
Ospedale Vito Fazzi, U.O. Di Cardiologia
Lecce, LE 73100, Italy
Ospedale Cardinale Panico - U.O. Cardiologia UTIC
Tricase, LE 73039, Italy
Ospedale Villamarina, Cardiologia E Utic
Piombino, LI 57025, Italy
Ospedale Civico, Cardiologia 2
Codogno, LO 26845, Italy
Ospedale Santa Croce, Ss Di Cardiologia
Castelnuovo Di Garfagnana, LU 55032, Italy
Nuovo Ospedale Versilia, Sc Cardiologia
Lido Di Camaiore, LU 55043, Italy
Ospedale Campo Di Marte, U.O. Di Cardiologia
Lucca, LU 55100, Italy
Ospedale San Gerardo, U.O. Cardiologia-Utic
Monza, MB 20900, Italy
Policlinico Di Monza, Uo Cardiol. Clinica E Scompenso Cardiaco
Monza, MB 20900, Italy
P.O. Sant'Agata Di Militello, U.O. Cardiologia -Utic
Sant'agata Di Militello, ME 98076, Italy
Ospedale Di Cernusco Sul Naviglio, U. O. Di Cardiologia E Ucc
Cernusco Sul Naviglio, MI 20063, Italy
Ospedale Bassini, U.O. Cardiologia E Utic
Cinisello Balsamo, MI 20092, Italy
Ospedale Civile, Utic - Cardiologia
Legnano, MI 20025, Italy
Ospedale Civile Fornaroli, U.O. Cardiologia
Magenta, MI 20013, Italy
Ospedale Fatebenefratelli e Oftalmico - Cardiologia e UCC
Milano, MI 20121, Italy
Ospedale Maggiore Policlinico, Divisione Di Cardiologia
Milano, MI 20122, Italy
Istituto Clinico Citta' Studi, U.O. Cardiologia
Milano, MI 20131, Italy
Centro Cardiologico Monzino - Terapia Intensiva Cardiologica UTIC
Milano, MI 20138, Italy
Ospedale San Paolo, Divisione Di Cardiologia
Milano, MI 20142, Italy
Ospedale San Luca-Centro Auxologico, U.O. Cardiologia
Milano, MI 20149, Italy
Ospedale L. Sacco, Divisione Di Cardiologia
Milano, MI 20157, Italy
Ospedale Niguarda, Cardiologia 1 - Emodinamica
Milano, MI 20162, Italy
Irccs Policlinico Multimedica, U.O. Cardiologia/Ucc
Sesto San Giovanni, MI 20099, Italy
Ospedale Di Vizzolo Predabissi, Uo Cardiologia E Ucc
Vizzolo Predabissi, MI 20077, Italy
Ospedali Destra Secchia, Cardiologia E Utic
Pieve Di Coriano, MN 46020, Italy
Ospedale Madonna Delle Grazie, U.O. Cardiologia-Utic-Angiologia
Matera, Mount 75100, Italy
Ospedale Giovanni Paolo Ii, Cardiologia Utic
Policoro, Mount 75025, Italy

Showing the first 100 of 203 sites.

References and documents

Publications

De Luca L, Leonardi S, Smecca IM, Formigli D, Lucci D, Gonzini L, Tuccillo B, Olivari Z, Gulizia MM, Bovenzi FM, De Servi S; EYESHOT Investigators. Contemporary antithrombotic strategies in patients with acute coronary syndromes managed without revascularization: insights from the EYESHOT study. Eur Heart J Cardiovasc Pharmacother. 2015 Jul;1(3):168-78. doi: 10.1093/ehjcvp/pvv006. Epub 2015 Feb 24. PubMed 27533991 ↗
De Luca L, Musumeci G, Leonardi S, Gonzini L, Cavallini C, Calabro P, Mauro C, Cacciavillani L, Savonitto S, De Servi S; EYESHOT Investigators. Antithrombotic strategies in the catheterization laboratory for patients with acute coronary syndromes undergoing percutaneous coronary interventions: insights from the EmploYEd antithrombotic therapies in patients with acute coronary Syndromes HOspitalized in iTalian cardiac care units Registry. J Cardiovasc Med (Hagerstown). 2017 Aug;18(8):580-589. doi: 10.2459/JCM.0000000000000533. PubMed 28639987 ↗
De Luca L, Pennacchi M, Musumeci G, D'Ascenzo F, Gallo P, Rigattieri S, Granatelli A, Berti S, Gulizia MM, De Servi S, Bolognese L; a nome dei Ricercatori EYESHOT e SCOPE. [Temporal evolution of antithrombotic therapy use in patients with acute coronary syndromes undergoing percutaneous coronary intervention in Italy: comparison between the EYESHOT and SCOPE registries]. G Ital Cardiol (Rome). 2018 Feb;19(2):101-110. doi: 10.1714/2868.28941. Italian. PubMed 29531382 ↗
De Luca L, Leonardi S, Cavallini C, Lucci D, Musumeci G, Caporale R, Abrignani MG, Lupi A, Rakar S, Gulizia MM, Bovenzi FM, De Servi S; EYESHOT Investigators. Contemporary antithrombotic strategies in patients with acute coronary syndrome admitted to cardiac care units in Italy: The EYESHOT Study. Eur Heart J Acute Cardiovasc Care. 2015 Oct;4(5):441-52. doi: 10.1177/2048872614560505. Epub 2014 Nov 20. PubMed 25414322 ↗
De Luca L, Leonardi S, Tubaro M, Gonzini L, Lucci D, Trimarco B, Misuraca G, Ledda A, Gulizia MM, De Servi S; EYESHOT Investigators. Is the use of risk scores an indicator of guideline adherence for patients with acute coronary syndromes? Insights from the EYESHOT Registry. Int J Cardiol. 2015;187:80-3. doi: 10.1016/j.ijcard.2015.03.343. Epub 2015 Mar 24. No abstract available. PubMed 25828318 ↗

Updates

Tracking since Sep 25, 2026

No changes since tracking began. The registry record was last updated on Feb 3, 2021, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗

Registry details

Key details

Study ID: NCT02015624
Lead sponsor: Heart Care Foundation
Collaborators: Centro Servizi ANMCO S.r.l., AstraZeneca
Responsible party: Sponsor
First posted: Dec 19, 2013
Start date: Dec 2013
Primary completion: Mar 2014
Completion: Mar 2014
Last update: Feb 3, 2021

Study contacts

Stefano De Servi, MD

study chair · Ospedale Civile - Legnano

Leonardo De Luca, MD

study chair · European Hospital - Roma

Oversight

Data monitoring committee: No

View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Mar 2014. You cannot join it, but the record below documents what was studied.

Follow this study

Get an email when the registry record changes — status, dates, results — or when someone posts here.

Discussion

Questions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.

Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.

Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.

Other studies in this condition

Acute Coronary Syndrome→

Other studies from this sponsor

Heart Care Foundation

Start the discussion