A Phase 2 interventional study of supragingival irrigators containing chlorhexidine in Severe Neutropenia, Thrombocytopenia and Chemotherapy, sponsored by Mashhad University of Medical Sciences. Completed at 1 site in Iran, Islamic Republic of. Open to participants aged 12 Years to 60 Years. Per ClinicalTrials.gov, last updated 2013-11-01.
Sponsored by Mashhad University of Medical Sciences · Phase 2, Interventional, and Prevention
in this study , effectiveness of supragingival irrigators containing chlorhexidine is compared with routine oral health measures in patients with blood dyscrasia whom can not use effective oral health measures(e.g brushing ) due to their systemic condition(e,g,neutropenia ,thrombocytopenia,..)
Since some patients with hematologic malignancies cannot brush effectively and are at increased risk of bleeding and infection due to severe neutropenia and thrombocytopenia we want to access whether a none invasive method ( water jet systems containing chlorhexidine ) Can help this patients to get better oral health indexes in comparison with routine oral health measures in these type of patients.
697 studies on the registry are indexed under Thrombocytopenia; 153 are open to participants now.
This study's enrollment of 20 is below the median of 55 across 472 interventional studies indexed under Thrombocytopenia.
Browse Thrombocytopenia studies →Mashhad University of Medical Sciences is the lead sponsor of 90 studies on the registry; 3 are open to participants now.
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patients with a blood dyscrasia, severe neutropenia and thrombocytopenia, absence of periodontitis, absence of any oral mucosal lesion in onset of study, patient consent
Exclusion Criteria:
diabetes mellitus, observation of any side effect (resulted from the device), severe oral mucositis in intervention group(grade 3 and4 WHO), edentulousness, intolerance of device in severely malaise patients, patient death
patients used supra-gingival irrigators as an oral health measure
Device: supragingival irrigators containing chlorhexidine
patients in this group received routine oral health care protocols.
patients received irrigation by oxyjet supra gingival irrigators containing chlorhexidine for at least 3 minutes for all dentulous regions of jaws which was performed by researchers once daily.
Also known as: Oral-B Braun Oxyjet irrigators
improvement in oral health status
improvement of oral health was measured by oral health index simplified(OHI-S)
Time frame: 3 weeks
incidence of oral mucositis
incidence of mucositis due to Who criteria explored by clinical examination
Time frame: 3 weeks
This study is completed, as verified in Oct 2013. You cannot join it, but the record below documents what was studied.
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Mashhad University of Medical Sciences