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WithdrawnNCT01952925Updated Feb 19, 2019

Combined Afib Ablation and RA Denervation for the Maintenance of Sinus Rhythm and Management of Resistant Hypertension

An interventional study of Renal Artery denervation in Afib and Hypertension, sponsored by Oregon Health and Science University. Withdrawn at 1 site in United States. Open to participants aged 18 Years to 100 Years. Per ClinicalTrials.gov, last updated 2019-02-19.

Sponsored by Oregon Health and Science University · Not applicable, Interventional, and Treatment

Why this study was withdrawn
unable to obtain IRB approval
Phase
Not applicable
Study type
Interventional
Enrollment
0
Allocation
Not applicable
Ages
18 Years to 100 Years
Sex
All
01

Study summary

The purpose of this study is to perform renal artery denervation at the same time as atrial fibrillation ablation. RA denervation may reduce blood pressure, increase the chances of a successful atrial fibrillation ablation, and decrease the number of medications required to control blood pressure.

02

Conditions studied

  • Afib
  • Hypertension

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03

In context

Hypertension

6,689 studies on the registry are indexed under Hypertension; 964 are open to participants now.

Browse Hypertension studies →

Lead sponsor

Oregon Health and Science University is the lead sponsor of 676 studies on the registry; 136 are open to participants now.

Of its 49 completed or terminated interventional studies of FDA-regulated products, 36 (73%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 100 Years
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • Hypertensive patients scheduled for afib ablation
  • Patient taking one or more BP medication

Exclusion criteria

Exclusion Criteria:

-

05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrollment
0 participants (actual)

Study arms

  • Experimental
    Combined afib ablation and RA denervation

    Patients with atrial fibrillation and resistant hypertension will be enrolled and undergo a single procedure consisting of pulmonary vein isolation and renal artery denervation.

    Procedure: Renal Artery denervation

Interventions

  • ProcedureRenal Artery denervation

    RA denervation performed as part of afib ablation procedure

06

What researchers measure

Primary outcomes

  1. change in systolic blood pressure when measured at routine 1 and 3 month follow up appointments

    Time frame: 1 to 3 months

07

Study locations

1 site
  • Oregon Health & Science University
    Portland, Oregon 97239, United States
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Feb 19, 2019, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT01952925
Lead sponsor
Oregon Health and Science University
Responsible party
Charles Henrikson, MD (Associate Professor, Knight Cardiovascular Institute, Oregon Health and Science University) — Principal investigator
First posted
Sep 30, 2013
Start date
Mar 2019 (estimated)
Primary completion
Mar 2019 (estimated)
Completion
Mar 2019 (estimated)
Last update
Feb 19, 2019

Study contacts

Charles Henrikson, MD
principal investigator · Oregon Health and Science University

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is withdrawn, as verified in Feb 2019. You cannot join it, but the record below documents what was studied.

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