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Status unknownNCT01943877PROPOLISUpdated Sep 17, 2013

Propolis In The Treatment Of Periodontitis

An interventional study of scaling root planing and Propolis in Chronic Periodontitis, sponsored by Rajarajeswari Dental College & Hospital. Status unknown at 1 site in India. Open to participants aged 25 Years to 50 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2013-09-17.

Sponsored by Rajarajeswari Dental College & Hospital · Not applicable, Interventional, and Treatment

The sponsor has not verified this record recently (last verified Sep 2013), so the status shown — last known as Active, not recruiting — may be out of date.
Phase
Not applicable
Study type
Interventional
Enrollment
20
Allocation
Randomized
Ages
25 Years to 50 Years
Sex
All
01

Study summary

This study was conducted to evaluate by clinical and microbiological parameters the effect of locally delivered propolis as an adjunct to scaling and root planing in the treatment of chronic periodontitis.

Read the detailed description

Materials and Methods: 20 subjects diagnosed with chronic periodontitis were recruited to participate in split-mouth design and provided informed consent. Subgingival plaque sampling and clinical recording at baseline, 15 days and 1 month was performed. The patients received scaling and root planing, followed by Propolis administration subgingivally in the test sites. Significant differences between test and control were evaluated using the Mann-Whitney U test and Wilcoxon rank test.

02

Conditions studied

  • Chronic Periodontitis
03

In context

Periodontitis

1,635 studies on the registry are indexed under Periodontitis; 327 are open to participants now.

This study's enrollment of 20 is below the median of 45 across 1,191 interventional studies indexed under Periodontitis.

Browse Periodontitis studies →

Lead sponsor

This is the only study on the registry with Rajarajeswari Dental College & Hospital as lead sponsor.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
25 Years to 50 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

  • good general health
  • chronic periodontitis
  • minimum of 20 natural teeth with at least one pocket per quadrant
  • probing depth (PD) between 5 and 8 mm.

Exclusion criteria

Exclusion Criteria:

  • subgingival instrumentation within 3 months
  • antibiotic therapy within 3 months prior to the start of the study;
  • smokers
  • pregnant or nursing women
  • intolerance or allergy to honey products
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Single (Participant)
Enrollment
20 participants (actual)

Study arms

  • Experimental
    Propolis

    Procedure: scaling root planing · Drug: Propolis

  • Sham comparator
    scaling and root planing

    Procedure: scaling root planing

Interventions

  • Procedurescaling root planing

    scaling root planing

  • DrugPropolis

    experimental

06

What researchers measure

Primary outcomes

  1. Change in the probing pocket depth and clinical attachment level

    Time frame: three time points of baseline,2 weeks, 4 weeks

Secondary outcomes

  1. change in gingival index and microbiological changes

    Time frame: three time points baseline, 2 weeks, 4 weeks.

07

Study locations

1 site
  • Rajarajeswari Dental College and Hospital
    Bangalore, Karnataka 560060, India
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Sep 17, 2013, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT01943877
Lead sponsor
Rajarajeswari Dental College & Hospital
Responsible party
NEHAL N SANGHANI, mds (DR., Rajarajeswari Dental College & Hospital) — Principal investigator
First posted
Sep 17, 2013
Start date
Dec 2012
Primary completion
Aug 2013
Completion
Oct 2013 (estimated)
Last update
Sep 17, 2013

Oversight

Data monitoring committee
Yes
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in Sep 2013. You cannot join it, but the record below documents what was studied.

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