An observational study in Abdominal Aortic Aneurysm, Coronary Heart Disease NOS and Unheralded Corronary Death, sponsored by University College, London. Status unknown at 1 site in United Kingdom. Open to participants aged 30 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2013-09-09.
Sponsored by University College, London · Observational
Study of heterogeneity in associations between social deprivation and the initial presentation of 12 cardiovascular diseases.
This study is part of the CALIBER (Cardiovascular disease research using linked bespoke studies and electronic records) programme funded over 5 years from the NIHR and Wellcome Trust. The central theme of the CALIBER research is linkage of the Myocardial Ischaemia National Audit Project (MINAP) with primary care (GPRD) and other resources. The overarching aim of CALIBER is to better understand the aetiology and prognosis of specific coronary phenotypes across a range of causal domains, particularly where electronic records provide a contribution beyond traditional studies. CALIBER has received both Ethics approval (ref 09/H0810/16) and ECC approval (ref ECC 2-06(b)/2009 CALIBER dataset).
7,286 studies on the registry are indexed under Stroke; 2,007 are open to participants now.
This study's enrollment of 1,937,360 is above the median of 160 across 1,692 observational studies indexed under Stroke.
Browse Stroke studies →University College, London is the lead sponsor of 632 studies on the registry; 145 are open to participants now.
Of its 6 completed or terminated interventional studies of FDA-regulated products, 2 (33%) have results posted.
Counted across the registry records on this site, refreshed daily.
1,93 million patients registered in Clinical Practice Research Datalink (CPRD) practices
Exclusion Criteria:
Other: No treatment
Hazard ratios for the associations between social deprivation and initial presentation of 12 cardiovascular diseases.
Associations studied: * overall * by sex * by age group * in high risk groups (smokers, hypertensive disease, obese, diabetic, depression) * before and after the introduction of the Quality and Outcomes Framework in England
Time frame: Followed for the duration of general practice registration between January 1997 and March 2010, an expected average of 5 years
Lifetime cumulative incidence per quintile of social deprivation
Time frame: Followed for the duration of general practice registration between January 1997 and March 2010, an expected average of 5 years
Heterogeneity in associations across 12 cardiovascular diseases using the Tau-squared statistic and I-square statistics.
Time frame: Followed for the duration of general practice registration between January 1997 and March 2010, an expected average of 5 years
This study is status unknown, as verified in Sep 2013. You cannot join it, but the record below documents what was studied.
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University College, London