An interventional study of non-invasive ventilation and high-flow oxygen in Respiratory Failure, sponsored by Universitätsklinikum Hamburg-Eppendorf. Completed at 1 site in Germany. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2020-11-13.
Sponsored by Universitätsklinikum Hamburg-Eppendorf · Not applicable, Interventional, and Treatment
Bronchoscopy with broncho-alveolar lavage is a diagnostic tool in patients with pneumonia. Especially patients with acute or chronic pulmonary diseases are at risk of respiratory failure during or after bronchoscopy. It is known that in these cases bronchoscopy can be performed safely using non-invasive ventilation. It seems probable that high-flow oxygen, which is used in the treatment of patients with hypoxemic respiratory failure, is equally effective in preventing the development of respiratory failure during fiberoptic bronchoscopy while improving patient comfort. In this prospective randomised study the safety of high-flow oxygen is compared with non-invasive ventilation in patients with hypoxemic respiratory failure undergoing fiberoptic bronchoscopy.
1,650 studies on the registry are indexed under Respiratory Insufficiency; 296 are open to participants now.
This study's enrollment of 40 is below the median of 55 across 1,043 interventional studies indexed under Respiratory Insufficiency.
Browse Respiratory Insufficiency studies →Universitätsklinikum Hamburg-Eppendorf is the lead sponsor of 403 studies on the registry; 83 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Performance of bronchoscopy during non-invasive ventilation.
Device: non-invasive ventilation · Procedure: fiberoptic bronchoscopy
Performance of bronchoscopy during high-flow oxygen therapy.
Device: high-flow oxygen · Procedure: fiberoptic bronchoscopy
non-invasive ventilation via face mask
high-flow oxygen via nasal cannula
fiberoptic bronchoscopy including broncho-alveolar lavage
Mean decrease in the saturation of oxygen (SpO2) during bronchoscopy.
Time frame: during fiberoptic bronchoscopy
Changes in blood gases after the completion of fiberoptic bronchoscopy.
Time frame: 1 hour after the completion of bronchoscopy
Requirement of intubation after the completion of bronchoscopy.
Time frame: 8 hours after the completion of bronchoscopy
This study is completed, as verified in Nov 2020. You cannot join it, but the record below documents what was studied.
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Universitätsklinikum Hamburg-Eppendorf