An interventional study of Conservative Management and Operative Management in Appendicitis, sponsored by Children's Hospital of Eastern Ontario. Terminated at 1 site in Canada. Open to participants aged Up to 18 Years. Per ClinicalTrials.gov, last updated 2016-11-10.
Sponsored by Children's Hospital of Eastern Ontario · Not applicable, Interventional, and Treatment
Appendicitis is one of the most common surgical problems in children, with 20-35% of patients having perforated by the time they present to a doctor. In these cases, the patient is often treated non-surgically with antibiotics. Once a patient has improved, it is not known whether it is better to perform an interval appendectomy (IA) or to continue a watchful waiting approach. The purpose of this trial is to determine if expectant nonoperative management (watchful waiting) is not inferior compared to IA management after successful conservative treatment of appendiceal mass at admission.
412 studies on the registry are indexed under Appendicitis; 62 are open to participants now.
This study's enrollment of 5 is below the median of 111 across 246 interventional studies indexed under Appendicitis.
Browse Appendicitis studies →Children's Hospital of Eastern Ontario is the lead sponsor of 83 studies on the registry; 9 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Children randomized to conservative management will be seen in the clinic 6-10 weeks after discharge and phoned to follow up every 3 month for a total follow-up of a year. Family will be instructed to come back to the hospital or call the treating physician if the child develops any abdominal pain or fever.
Procedure: Conservative Management
Children randomized to IA will be scheduled for an interval appendectomy 6-10 weeks after discharge, and will be seen in the clinic 6-8 weeks following the interval appendectomy and phoned for follow-up every 3 month for a total of one year.
Procedure: Operative Management
Recurrent appendicitis for the conservative group
Time frame: During a year of follow-up
Operative complications for the operative group
Time frame: During a year of follow-up
Duration of hospital stay
Time frame: This is the patients' original hospital stay, and re-admission for interval appendectomy when applicable, an expected average of 5 days
This study is terminated, as verified in Nov 2016. You cannot join it, but the record below documents what was studied.
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Children's Hospital of Eastern Ontario