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WithdrawnNCT01762007Updated May 6, 2021

The Change of the Detrusor Thickness After Hypospadias Repair - Comparison With the Normal Control Group

An observational study in Hypospadias, sponsored by Yonsei University. Withdrawn at 1 site in Korea, Republic of. Open to male participants aged Up to 5 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2021-05-06.

Sponsored by Yonsei University · Observational

Why this study was withdrawn
Due to difficulty in purchasing reagents, study canceled without subject registration
Study type
Observational
Model
Case-control
Time perspective
Prospective
Enrollment
0
Ages
Up to 5 Years
Sex
Male
01

Study summary

Even successfully managed hypospadias without any complication, voiding problem could be developed due to the increased urethral resistance. The investigators are trying to analyze the effect of hypospadias operation on voiding function by checking the detrusor thickness and urinary nerve growth factor.

02

Conditions studied

  • Hypospadias

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Keywords

  • hypospadias, bladder outlet obstruction, ultrasonography
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In context

Hypospadias

131 studies on the registry are indexed under Hypospadias; 34 are open to participants now.

Browse Hypospadias studies →

Lead sponsor

Yonsei University is the lead sponsor of 1,387 studies on the registry; 232 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
Up to 5 Years
Sexes eligible
Male
Accepts healthy volunteers
Yes
Sampling method
Non-probability sample

Study population

Group 1: 13 patients with 6Mo-2Yr old penile hypospadias patients before operation Group 2: 13 patients with 6Mo-2Yr old male patients without hypospadias Group 3: 15 patients with penile hypospadias patients under the age of 5 Yr who got tubularized incised plate operation at out institution at the age between 6Mo and 2Yr old and more than 1 Yr have passed Group 4: 15 patients with 2Yr-5Yr old male patients without hypospadias

Inclusion criteria

\<Group 1>

  1. 6Mo-2Yr old penile hypospadias patients before operation \<Group 2>
  2. 6Mo-2Yr old male patients without hypospadias \<Group 3>
  3. penile hypospadias patients under the age of 5 Yr who got tubularized incised plate operation at out institution at the age between 6Mo and 2Yr old and more than 1 Yr have passed \<Group 4>
  4. 2Yr-5Yr old male patients without hypospadias1. 0-3 year old children without any abnormality of urinary tract

Exclusion criteria

Exclusion Criteria:

\<Group 1, 2, 4>

  1. patients with history of urethral operation, febrile urinary tract infection, neurogenic abnormality om operation \<Group 3>
  1. patients with history of urethral operation other than hypospadias repair, febrile urinary tract infection, neurogenic abnormality
  2. patients with development urethra-cutaneous fistula
05

Study design

Observational model
Case-control
Time perspective
Prospective
Enrollment
0 participants (actual)
Patient registry
No

Groups and cohorts

  • 6Mo-2Yr old penile hypospadias patients before operation
  • 6Mo-2Yr old male patients without hypospadias
  • penile hypospadias patients under the age of 5 Yr

    penile hypospadias patients under the age of 5 Yr who got tubularized incised plate operation at out institution at the age between 6Mo and 2Yr old and more than 1 Yr have passed

  • 2Yr-5Yr old male patients without hypospadias
06

What researchers measure

Primary outcomes

  1. Detrusor thickness

    Time frame: immediate analysis of detrusor thickness at the enrollment time of this study

Secondary outcomes

  1. urinary nerve growth factor level

    Time frame: immediate analysis of urinary nerve growth factor level at the enrollment time of this study

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Study locations

1 site
  • Sang Won
    Seoul, 120-752, Korea, Republic of
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on May 6, 2021, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT01762007
Lead sponsor
Yonsei University
Responsible party
Sponsor
First posted
Jan 7, 2013
Start date
Nov 2012
Primary completion
Jul 2013 (estimated)
Completion
Jul 2013 (estimated)
Last update
May 6, 2021

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is withdrawn, as verified in May 2021. You cannot join it, but the record below documents what was studied.

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