ClinicalTrials.gg
Status unknownNCT01615003Updated Jan 14, 2014

The Study of MicroRNA Genomics of Blood Stasis Syndrome and of Coronary Heart Disease

A Phase 2 interventional study of Xuesaitong soft capsule and Xuesaitong soft capsule Placebo in Coronary Heart Disease, Unstable Angina and Blood Stasis Syndrome, sponsored by Guang'anmen Hospital of China Academy of Chinese Medical Sciences. Status unknown at 1 site in China. Open to participants aged 30 Years to 75 Years. Per ClinicalTrials.gov, last updated 2014-01-14.

Sponsored by Guang'anmen Hospital of China Academy of Chinese Medical Sciences · Phase 2, Interventional, and Treatment

The sponsor has not verified this record recently (last verified Jan 2014), so the status shown — last known as Recruiting — may be out of date.

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Phase
Phase 2
Study type
Interventional
Enrollment
70
Allocation
Randomized
Ages
30 Years to 75 Years
Sex
All
01

Where this study stands

Counted across the records on this site · 2026-11-13

Among 222 studies in Coronary Disease with a site in China — 67 open to participants now, 76 under way, 2 of them phase 3. Coronary Disease · China.

Planned enrollment
115th of 140
70 · median 220
Started
2012
with 20 others
Phase 2
6 of 222
2 open now
Registered
29th of 222
by date

Among the 222 studies in Coronary Disease with a site in China, this one is the 115th largest by planned enrollment of the 140 interventional ones that give a count, is one of 21 that started in 2012, is one of 6 in phase 2, and was the 29th registered.

Coronary Disease

1,521 studies on the registry are indexed under Coronary Disease; 168 are open to participants now.

Browse Coronary Disease studies →

Open to participants now

67 of the 222 studies in Coronary Disease with a site in China are open now. Recruiting first, the newest first:

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All 67 open studies →

A study can be open while its sites in China have not opened yet or have stopped. Only those recruiting at a site in China →

Who these studies take

Of the 106 Coronary Disease studies recruiting now, 64 (60%) set no upper age limit and 19 (18%) stop at 75 or younger; 8 take children under 18; 10 take healthy volunteers.

This study: 30 Years to 75 Years · all sexes · no healthy volunteers.

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02

Study summary

In this study, typical cases of blood stasis syndrome of coronary heart disease are selected, by using microRNA chip, cDNA microarray and other bioinformatics technologies to filter and verify related miRNA and its target gene of Coronary Heart disease. Meanwhile, intervene by Xuesaitong soft capsules to investigate related miRNA and its target gene of Coronary Heart disease.

03

Conditions studied

  • Coronary Heart Disease
  • Unstable Angina
  • Blood Stasis Syndrome

Keywords

  • MicroRNA
  • coronary heart disease
  • unstable angina
  • blood stasis syndrome
  • Xuesaitong soft capsule
04

Who can participate

Ages eligible
30 Years to 75 Years
Sexes eligible
All
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Clinical diagnosis of coronary angiography unstable angina
  • Clinical diagnosis of unstable angina
  • Age of 30 to 75 years old
  • Not use thrombolysis, dilate coronary drugs within two weeks
  • Tongue dark
  • Sign the consent

Exclusion criteria

Exclusion Criteria:

  • Severe valvular heart disease
  • Insulin-dependent diabetes
  • mental disease
  • Combined with severe liver, kidney, hematopoietic system disorder
  • Patients with malignant tumors
  • Pregnancy or breast-feeding women
  • Recent history of trauma
  • Drug allergy
05

Study design

Phase
Phase 2
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Quadruple (Participant, Care provider, Investigator, Outcomes assessor)
Enrollment
70 participants (estimated)

Study arms

  • Experimental
    Xuesaitong soft capsule group

    Patients who confirmed by coronary angiography and diagnosed blood stasis syndrome of coronary heart disease are given conventional Western medicine treatment and Xuesaitong soft capsule.

    Drug: Xuesaitong soft capsule

  • Placebo comparator
    control group

    Patients who confirmed by coronary angiography and diagnosed blood stasis syndrome of coronary heart disease are given conventional Western medicine treatment and placebo.

    Drug: Xuesaitong soft capsule Placebo

Interventions

  • DrugXuesaitong soft capsule

    Xuesaitong soft capsule, soft capsule, Ingredients:PNS, Specification:0.33 per bag, once take two pills and twice a day during a month.

  • DrugXuesaitong soft capsule Placebo

    Xuesaitong soft capsule Placebo, soft capsule, once take two pills and twice a day during a month.

06

What researchers measure

Primary outcomes

  1. the change of Cycle threshold of relational microRNA in coronary artery disease with unstable angina

    The change of Cycle threshold of relational microRNA in coronary artery disease with unstable angina by real RT-PCR.

    Time frame: 1 month

07

Study locations

1 of 1 sites recruiting
  • Guang'an men Hispital
    Beijing, Beijing 100000, China
    Recruiting
    • Fei Teng, master · Contactecho-teng@126.com · 13581985462
    • Gui Yu, master · Contact13488835663
    • Jie Wang, doctor · Principal investigator
08

Timeline

Tracking since Sep 25, 2026
Not marked actual or estimatedDates not marked actual or estimated

The record gives a start of May 2012, a primary completion of Jul 2014 and a completion of Dec 2014. It does not say whether these dates are actual or estimated.

How these figures are worked out, and which studies are left out of them.

Registered
May 28, 2012
First posted
Jun 8, 2012
Start
May 2012
Primary completionEst.
Jul 2014
CompletionEst.
Dec 2014
Last update
Jan 14, 2014
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Jan 14, 2014, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT01615003
Responsible party
Sponsor
First posted
Jun 8, 2012
Start date
May 2012
Primary completion
Jul 2014 (estimated)
Completion
Dec 2014 (estimated)
Last update
Jan 14, 2014

Study contacts

Fei Teng, master
Contact
echo-teng@126.com
13581985462

Oversight

Data monitoring committee
Yes
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in Jan 2014. You cannot join it, but the record below documents what was studied.

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