A Phase 2 interventional study of preseptal injection of botulinum toxin type A and pretarsal injection of Botulinum toxin type A in Hemifacial Spasm, sponsored by Khon Kaen University. Status unknown at 1 site in Thailand. Open to participants aged 20 Years to 70 Years. Per ClinicalTrials.gov, last updated 2012-03-28.
Sponsored by Khon Kaen University · Phase 2, Interventional, and Treatment
The purpose of this study is to determine whether pretarsal and preseptal techniques of Botulinum toxin type A injection have any effect on tear functions.
Botulinum toxin type A has been used for hemifacial spasm since 1986. of Botulinum toxin type A can be subcutaneously injected at pretarsal or preseptal portion of orbicularis muscle. Blepharoptosis has been reported less frequently with pretarsal technique, however dry eye was noticed in one patient treated with pretarsal botulinum toxin type A for cosmetic purpose.
23 studies on the registry are indexed under Hemifacial Spasm; 3 are open to participants now.
This study's planned enrollment of 26 is below the median of 61 across 11 interventional studies indexed under Hemifacial Spasm.
Browse Hemifacial Spasm studies →Khon Kaen University is the lead sponsor of 161 studies on the registry; 24 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Drug: preseptal injection of botulinum toxin type A
Drug: pretarsal injection of Botulinum toxin type A
botulinum toxin type A (Botox)2.5 units, 5 points
Also known as: Botox
Botulinum toxin type A 2,5 units, 5 points
Also known as: Botox
tear break up time
unit of measure; minutes
Time frame: change from baseline in tear break up time at 12 weeks
schirmer's test
units of measurement; millimeters
Time frame: change from baseline of schirmer's test at 12 weeks
This study is status unknown, as verified in Mar 2012. You cannot join it, but the record below documents what was studied.
Get an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.
Studies of the drug tested here: Onabotulinum toxin A