A Phase 1 interventional study of household water treatment in Acute Diarrhoea, sponsored by Haramaya Unversity. Completed at 1 site in Ethiopia. Open to participants aged 1 Month to 59 Months. Per ClinicalTrials.gov, last updated 2012-01-24.
Sponsored by Haramaya Unversity · Phase 1, Interventional, and Prevention
The Millenium development goals (MDGs) call for reducing by half the proportion of people without sustainable access to safe drinking water. This goal was adopted in large part because safe drinking water has been seen as critical to fighting diarrheal disease. Source protection is considered the main intervention area to achieve this goal. However, research worldwide that has shown that even drinking water which is safe at the source is subject to frequent and extensive fecal contamination during collection, storage and use in the home. This contamination is through the introduction of cups, dippers or hands, contamination by flies, cockroaches, and rats. Even piped water supplies of adequate microbial quality can pose infectious disease risks if they become contaminated due to unsanitary collection, storage conditions and practices within households.
To reduce this problem, point-of-use water treatment has been advocated as a means to substantially decrease the global burden of diarrhea and to contribute to the MDGs. However, research indicates that there are many unanswered questions around Household water treatment (HWT) that require small or medium scale epidemiological studies and randomized controlled trials, especially with regard to effectiveness, acceptability and identifying suitable target populations. Some of the most urgent questions to be resolved are:(1) How much of the currently cited disease reduction of HWT is due to bias? (2) What is the effect of HWT on nutritional status (weight gain and growth)?(3) At which populations should HWT be targeted? (4) Is it acceptable and sustainable in poor communities where the risk of diarrheal disease is high.
hypothesis: Do household water treatment with chlorine reduce diarrhea among underfive children? hypothesis: Do household water treatment with chlorine acceptable in the community?
852 studies on the registry are indexed under Diarrhea; 78 are open to participants now.
This study's enrollment of 845 is above the median of 136 across 713 interventional studies indexed under Diarrhea.
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Exclusion Criteria:
household water treatment with 1.25% sodium hypochlorite
Other: household water treatment
Usual practice (the use of "Jerrican" for water storage, which is considered as safe storage)
household water treatment with 1.25% sodium hypochlorite
Also known as: 1.25% sodium hypochlorite
To assess the prevalence of diarrhea among under five children
weekly visit of the household for the presence of diarrhoea among underfive for four months in both the intervention and control groups
Time frame: four months
To assess the weight gain among the intervention and control groups of under five children
This is designed to assess whether there is weight gain (objective outcome) in children assigned to the intervention group compared to the control group. It is supplement to the prevalence of diarrhea which is subjective outcome for this study
Time frame: At the beginning and end of the study ( 4 months interval)
Residual chlorine test
The use of the intervention (1.25% hypochlorite) is confirmed by the testing the residual chlorine weekly for for months from each household assigned in the intrevention group
Time frame: four months
This study is completed, as verified in Jan 2012. You cannot join it, but the record below documents what was studied.
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Haramaya Unversity