Status unknownNCT01310907Updated Mar 9, 2011

Identify the Genes Polymorphisms Related to Non-familial Bradyarrhythmia

An observational study in Bradyarrhythmia, sponsored by China Medical University Hospital. Status unknown at 2 sites in Taiwan. Per ClinicalTrials.gov, last updated 2011-03-09.

Sponsored by China Medical University Hospital · Observational

The sponsor has not verified this record recently (last verified Mar 2011), so the status shown — last known as Recruiting — may be out of date.

Study type: Observational
Enrollment: 400
Sex: All

Study summary

Bradyarrhythmia, including sinus node dysfunction and atrioventricular block, is a major cause necessitating pacemaker implantation. In contrast to familial bradyarrhythmia known as by mutations at particular ion channels, limited information is available for the mechanistic study in non-familial bradyarrhythmia.

Possible gene polymorphisms related to non-familial bradyarrhythmia were studied. Comparison of multi-locus analysis and single-locus analysis will be analyzed between the cases and controls. Functional studies will perform to clarify the results of association study.

Conditions studied

Bradyarrhythmia

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Bradycardia 306

In context

Bradycardia

306 studies on the registry are indexed under Bradycardia; 69 are open to participants now.

This study's planned enrollment of 400 is above the median of 257 across 129 observational studies indexed under Bradycardia.

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Lead sponsor

China Medical University Hospital is the lead sponsor of 464 studies on the registry; 116 are open to participants now.

Counted across the registry records on this site, refreshed daily.

Who can participate

Ages eligible: Child (0–17), Adult (18–64), Older adult (65+)
Sexes eligible: All
Accepts healthy volunteers: Yes
Sampling method: Probability sample

Study population

The case group include 200 patients and the control group include 200 patients.

Inclusion criteria

The patients with non-familial bradyarrhythmia

Exclusion criteria

Exclusion Criteria:

Familial bradyarrhythmia Reversible bradyarrhythmia Bradyarrhythmia after open heart surgery and severe organic heart diseases

Study design

Enrollment: 400 participants (estimated)

Groups and cohorts

sinus node dysfunction
Atrioventricular block
control

Study locations

2 of 2 sites recruiting

China Medical University Hospital
Taichung, 404, Taiwan
- Jan-Yow Chen, MD · Contact · janyow@ms77.hinet.net · +88622052121
- Jan-Yow Chen, MD · Principal investigator
Recruiting
China Medical University Hospital
Taichung, 404, Taiwan
- Jan-Yow Chen, MD · Contact · janyow@ms77.hinet.net · +886-4-22052121
- Jan-Yow Chen, MD · Principal investigator
Recruiting

References and documents

Publications

Mangrum JM, DiMarco JP. The evaluation and management of bradycardia. N Engl J Med. 2000 Mar 9;342(10):703-9. doi: 10.1056/NEJM200003093421006. No abstract available. PubMed 10706901 ↗

Updates

Tracking since Sep 25, 2026

No changes since tracking began. The registry record was last updated on Mar 9, 2011, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗

Registry details

Key details

Study ID: NCT01310907
Lead sponsor: China Medical University Hospital
Collaborators: China Medical University, China
First posted: Mar 9, 2011
Start date: Feb 2011
Last update: Mar 9, 2011

Study contacts

Jan-Yow Chen, MD

Contact

janyow@ms77.hinet.net

+422052121 ext. 2311

Jan-Yow Chen, MD

principal investigator · China Medical University Hospital

View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in Mar 2011. You cannot join it, but the record below documents what was studied.

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