An observational study in Open Angle Glaucoma, sponsored by Lithuanian University of Health Sciences. Completed at 1 site in Lithuania. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2012-01-12.
Sponsored by Lithuanian University of Health Sciences · Observational
To evaluate whether add-on to prostaglandin therapy with twice a day (bid) dorzolamide is statistically superior to twice a day (bid) timolol with regard to increasing ocular blood flow
Hypotensive treatments for glaucomatous optic neuropathy (GON), depending on their chemical composition can influence the ocular circulation independent of intraocular pressure (IOP) reduction. It is therefore important not only to identify ocular blood flow deficits in GON, but also document the influence of GON treatments on the ocular circulation
1,818 studies on the registry are indexed under Glaucoma; 231 are open to participants now.
This study's enrollment of 35 is below the median of 103 across 454 observational studies indexed under Glaucoma.
Browse Glaucoma studies →Lithuanian University of Health Sciences is the lead sponsor of 102 studies on the registry; 31 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Regular visitors of Eye Clinic of Lithuania University of Health Science hospital
Exclusion Criteria:
timolol or dorzolamide add on latanoprost monotherapy
Device: Color Doppler Imaging
Color Doppler imaging (CDI) system for measurements of blood flow in the ophthalmic (OA), central retinal (CRA), and nasal (NPCA) and temporal (TPCA) posterior ciliary arteries. In each vessel, peak systolic velocity (PSV) and end diastolic velocity (EDV) were determined, and Pourcelot's resistive index will be calculated (RI = (PSV-EDV)/PSV).
Also known as: timololum maleate, dorzolamidum, latanoprostum
Ocular Color Doppler Imaging
Color Doppler Imaging * Nasal post ciliary artery (NPCA) * Temporal posterior ciliary artery (TPCA) * Ophthalmic artery (OA) * Central retinal artery (CRA)
Time frame: 8 AM; 8 PM
IOP, BP, OPP (mean, fluctuations, amplitude)
IOP, BP, OPP (mean, fluctuations, amplitude) Goldmann applanation tonometry Brachial artery pressure and radial pulse
Time frame: 8 AM-12AM-4PM-8PM
This study is completed, as verified in Jan 2012. You cannot join it, but the record below documents what was studied.
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Lithuanian University of Health Sciences