An observational study in Ankylosing Spondylitis (AS) / Radiographic Axial SpA (r-axSpA), Non-radiographic Axial Spondyloarthritis (Nr-axSpA) and Axial Psoriatic Arthritis (axPsA), sponsored by Charite University, Berlin, Germany. Recruiting at 1 site in Germany. Per ClinicalTrials.gov, last updated 2021-10-12.
Sponsored by Charite University, Berlin, Germany · Observational
Among 13 studies in Spondylitis, Ankylosing by Charite University, Berlin, Germany — 1 open to participants now, 1 under way, none of them phase 3. Spondylitis, Ankylosing · Charite University, Berlin, Germany.
Among the 13 studies in Spondylitis, Ankylosing by Charite University, Berlin, Germany, this one is the only one that started in 2000, is one of 3 observational ones, and was the 10th registered.
531 studies on the registry are indexed under Spondylitis, Ankylosing; 98 are open to participants now.
This study's planned enrollment of 1,000 is above the median of 202 across 214 observational studies indexed under Spondylitis, Ankylosing.
Browse Spondylitis, Ankylosing studies →1 of the 13 studies in Spondylitis, Ankylosing by Charite University, Berlin, Germany is open now, in 1 country. Each count lists the studies.
Of the 63 Spondylitis, Ankylosing studies recruiting now, 25 (40%) set no upper age limit and 32 (51%) stop at 75 or younger; 10 take children under 18; 15 take healthy volunteers.
This study: all sexes · no healthy volunteers.
The full table on the hub →13 studies; the count open now beside each. This study's row is marked.
First in 2000; this study’s year is marked. 1 started in 2000.
Median enrollment 38 across the 10 interventional studies, 992 across the 3 observational. Of the 4 that completed or were terminated, 0 (0%) have results posted.
Charite University, Berlin, Germany is the lead sponsor of 857 studies on the registry; 129 are open to participants now.
None of the studies under way reaches primary completion within a year.
Among the 13 studies in Spondylitis, Ankylosing by Charite University, Berlin, Germany, from their registry updates:
Nothing recorded among them since 2026-09-25.
The German Spondyloarthritis Inception cohort (GESPIC) was started 2000 as a prospective, longitudinal, multicentre, nationwide study in Germany on patients with early SpA including ankylosing spondylitis (AS, also known as radiographic axial spondyloarthritis) and non-radiographic axial SpA. The objectives of GESPIC are to learn about the course of SpA during the very early stage of the disease, to appropriately assess the outcome including radiographic progression of patients after several years of follow-up, to identify outcome predictors, to assess quality of life, function, and costs (direct and indirect costs). GESPIC has been recently expanded to recruit patients with other forms of SpA / conditions associated with SpA: acute anterior uveitis, Crohn's disease as well as with psoriasis / axial psoriatic arthritis.
Patients included in GESPIC are required to have a definite clinical diagnosis of axial SpA / juvenile SpA (currently only adult patients with radiographic axial SpA = ankylosing spondylitis - AS are recruited) or a definite diagnosis of Crohn's disease or a definite diagnosis of acute anterior uveitis or a definite diagnosis of psoriatic arthritis with axial involvement.
Main inclusion Criteria:
Ankylosing spondylitis according to the modified New York criteria or with the clinical diagnosis of AS/r-axSpA fulfilling the ASAS Classification Criteria AND the mNY criteria plus having the indiaction for starting a bDMARD therapy according to the treating rheumatologist
Patients with clinical characteristics of axial SpA but not fulfilling the modified New York criteria for which radiographic sacroiliitis is essential or with the clinical diagnosis of nr-axSpA fulfilling the ASAS Classification Criteria not fulfilling the mNY criteria and the indiaction for starting a bDMARD therapy according to the treating rheumatologist
Patients with juvenile spondyloarthritis (juvenile ankylosing spondylitis, juvenile non-AS-spondyloarthritis).
Patients with Crohn's disease
Patients with acute anterior uveitis
Patients with the clinical diagnosis of psoriatic arthritis with axial involvement (sacroiliac joints and/or spine) (axPsA)
The record gives a start of Jul 2000, a primary completion of Jul 2030 and a completion of Jul 2030. It does not say whether these dates are actual or estimated.
How these figures are worked out, and which studies are left out of them.
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Charite University, Berlin, Germany →