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CompletedNCT01192425EXPLOREUpdated Jun 24, 2026

Paroxysmal Nocturnal Hemoglobinuria (PNH), Level of CD59 on Red and White Blood Cells in Bone Marrow Failure Syndromes

An observational study in Hemoglobinuria, sponsored by Alexion Pharmaceuticals, Inc.. Completed. Open to participants aged 10 Years and older. Per ClinicalTrials.gov, last updated 2026-06-24.

Sponsored by Alexion Pharmaceuticals, Inc. · Observational

Study type
Observational
Model
Other
Time perspective
Prospective
Enrollment
5,580
Ages
10 Years and older
Sex
All
01

Study summary

Examine red and white blood cells of PNH patients with bone marrow failure syndromes.

02

Conditions studied

  • Hemoglobinuria

Keywords

  • PNH clone cells
  • Aplastic Anemia
  • AA
  • Myelodysplastic Syndromes
  • MDS
  • bone marrow failure syndromes
  • FLAER
  • Paroxysmal Nocturnal Hemoglobinuria
03

Who can participate

Ages eligible
10 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Probability sample

Study population

Patients at least 10 years of age with aplastic anemia, myelodyplastic syndromes or other bone marrow failure syndromes.

Inclusion criteria

  • At least 10 years of age.
  • Has aplastic anemia, myelodysplastic syndromes or other bone marrow failure syndromes

Exclusion criteria

Exclusion Criteria:

  • Has any condition that might interfere with the patient's participation
04

Study design

Observational model
Other
Time perspective
Prospective
Enrollment
5,580 participants (actual)
05

Study locations

No study locations are listed for this record.

06

Registry details

Key details

Study ID
NCT01192425
Lead sponsor
Alexion Pharmaceuticals, Inc.
Responsible party
Sponsor
First posted
Sep 1, 2010
Start date
Sep 1, 2010
Primary completion
Sep 2010
Completion
Sep 2010
Last update
Jun 24, 2026

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

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This study is completed, as verified in Jun 2026. You cannot join it, but the record below documents what was studied.

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