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Hemoglobinuria, Paroxysmal clinical trials

The registry lists 191 studies for Hemoglobinuria, Paroxysmal across more than 10 countries. 49 are recruiting or about to start. 156 of them are mainly about Hemoglobinuria, Paroxysmal (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10.

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Status

Completed
102
Recruiting
30
Active, not recruiting
20
Not yet recruiting
15
Terminated
13
Status unknown
5

Phase

Phase 2
70
Phase 3
50
Phase 1
29
Phase 4
3

Where

United States
68
China
51
United Kingdom
45
Italy
33
Korea, Republic of
33
France
28

Who runs them

Alexion Pharmaceuticals, Inc. (32) · Novartis Pharmaceuticals (16) · Regeneron Pharmaceuticals (10) · Wuhan Createrna Science and Technology Co., Ltd (9) · BioCryst Pharmaceuticals (6) · Apellis Pharmaceuticals, Inc. (6) · National Heart, Lung, and Blood Institute (NHLBI) (6) · Chengdu Suncadia Medicine Co., Ltd. (6)

What is being tested here

Drugs under test in Hemoglobinuria, Paroxysmal studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

DrugOpenPhase 3All
Lanoracopan539
Ruxoprubart303
Cyclophosphamide206
Pozelimab236
Cemdisiran225
HSK39297214
NTQ5082223
FXS6837222
Iptacopan157
Danicopan136

Drug classes tested here Alkylating agents 2 open · Antimetabolites 6

Coming up

17phase 3 studies under way
19studies finish main data collection within a year6 of them phase 3

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

The 10 nearest, phase 3 first

Who these studies take

Of the 30 Hemoglobinuria, Paroxysmal studies recruiting now, 14 (47%) set no upper age limit and 12 (40%) stop at 75 or younger. 12 (40%) take children under 18. 1 (3%) are for women only and 0 (0%) for men only; 4 (13%) take healthy volunteers.

Recruiting studies that take each age, of 30
AgeWomenMen
1010 (33%)9 (30%)
1828 (93%)27 (90%)
3027 (90%)26 (87%)
4027 (90%)26 (87%)
5026 (87%)25 (83%)
6525 (83%)24 (80%)
7523 (77%)22 (73%)
8516 (53%)15 (50%)

Across all 191 studies, recruiting or not: 32% stop at 75 or younger and 18% at 65; 25% take children; 1% are for women only and 1% for men only; 11% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

How long Hemoglobinuria, Paroxysmal studies take

Of 35 phase 3 interventional studies under Hemoglobinuria, Paroxysmal, half reached primary completion within 23 months of starting, counting those still running.

Start to primary completionEvery sponsorIndustryNon-industry
Phase 113 mo5–34 · 19 studies——
Phase 224 mo12–80 · 34 studies16 mo11–25 · 26 studies—
Phase 323 mo15–41 · 35 studies23 mo15–41 · 35 studies—

Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out

What changed recently

From the registry's own updates since Oct 13, 2026.

Newly registered2

Studies

Recruiting first, then most recently updated. Showing 50 of 191. Browse all 191 → or search them.