CClinicalTrials.gg
WithdrawnNCT01169948Updated Mar 14, 2013

320 Multidetector Computed Tomography Prior to Coronary Artery Bypass Surgery

An observational study in Coronary Disease, sponsored by University of Edinburgh. Withdrawn at 1 site in United Kingdom. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2013-03-14.

Sponsored by University of Edinburgh · Observational

Why this study was withdrawn
Not funded.
Study type
Observational
Model
Case-only
Time perspective
Cross-sectional
Enrollment
0
Ages
18 Years and older
Sex
All
01

Study summary

Recent advances in technology have resulted in the development of scanners that can n image the heart arteries within 10 to 20 minutes but without the need for admission to hospital or insertion of catheters. This means that coronary heart disease may be more readily identified (or ruled out) and allow better diagnosis and treatment of patients with symptoms suggesting coronary heart disease. Here, we propose to assess the latest and most powerful scanners to see if it can accurately diagnose the extent of coronary artery disease and facilitate the planning of heart surgery.

02

Conditions studied

  • Coronary Disease

Keywords

  • Coronary disease
  • Coronary artery bypass
  • Cardiac surgery
  • Computed tomography
  • Coronary angiography
03

In context

Coronary Disease

2,839 studies on the registry are indexed under Coronary Disease; 311 are open to participants now.

Browse Coronary Disease studies →

Lead sponsor

University of Edinburgh is the lead sponsor of 393 studies on the registry; 64 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Outpatients awaiting cardiac surgery.

Inclusion criteria

  • patients who have undergone conventional coronary angiography and have been referred for coronary artery bypass surgery or valve replacement

Exclusion criteria

Exclusion Criteria:

  • age less than 18
  • pregnancy or breast feeding
  • inability to undergo computed tomography scanning
  • inability to give informed consent
  • severe renal failure (serum creatinine >250umol/l or estimated glomerular filtration rate \<15ml/min)
  • known allergy to iodinated contrast
05

Study design

Observational model
Case-only
Time perspective
Cross-sectional
Enrollment
0 participants (actual)

Groups and cohorts

  • Patients awaiting cardiac surgery

    Radiation: Computed tomography scan

Interventions

  • RadiationComputed tomography scan

    Computed tomography will be performed using a 320 multidetector computed tomography scanner and may include coronary calcium score, coronary angiography and myocardial perfusion scanning.

06

What researchers measure

Primary outcomes

  1. Coronary artery stenosis defined qualitatively by trained observers and quantitatively by computer software

    Time frame: 1 month

Secondary outcomes

  1. Myocardial perfusion defects defined qualitatively by trained observers and quantitatively by computer software

    Time frame: 1 month

07

Study locations

1 site
  • Royal Infirmary of Edinburgh
    Edinburgh, Scotland EH16 4SA, United Kingdom
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Mar 14, 2013, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT01169948
Lead sponsor
University of Edinburgh
Responsible party
Sponsor
First posted
Jul 26, 2010
Start date
Jun 2010
Last update
Mar 14, 2013

Study contacts

David E Newby, PhD BM DM
principal investigator · University of Edinburgh

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is withdrawn, as verified in Mar 2013. You cannot join it, but the record below documents what was studied.

Follow this study

Get an email when the registry record changes — status, dates, results — or when someone posts here.

Sign in to follow

Discussion

Questions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.

Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.

Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.

Start the discussion