An observational study in Age-related Cognitive Decline, sponsored by Palo Alto Veterans Institute for Research. Completed at 1 site in United States. Open to participants aged 45 Years to 100 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2017-02-28.
Sponsored by Palo Alto Veterans Institute for Research · Observational
The primary purpose of this study is to apply state-of-the-art Magnetic Resonance Imaging (MRI) and Magnetic Resonance Spectroscopic Imaging (MRSI) techniques to measure changes over time in the brain.
We expect that MRI and MRSI techniques will be a useful adjunct in research efforts to understand individual differences in performance of a complex attention-demanding task, such as flying a plane or driving a car. Other predictors of change in performance of a complex task may include simple tests of processing speed and working memory, past training and recent practice of the task, and genetic risk factors for degenerative brain disease. In this project, we will examine whether baseline MR measures are as useful as longitudinal MR measures in predicting amount of change over time in task performance.
This research is part of a long-term effort to achieve earlier identification of individuals at risk of decline and ultimately minimize loss of function.
3,843 studies on the registry are indexed under Cognitive Dysfunction; 1,099 are open to participants now.
This study's enrollment of 67 is below the median of 150 across 950 observational studies indexed under Cognitive Dysfunction.
Browse Cognitive Dysfunction studies →Palo Alto Veterans Institute for Research is the lead sponsor of 51 studies on the registry; 10 are open to participants now.
Counted across the registry records on this site, refreshed daily.
active healthy pilots
Exclusion Criteria:
MRI - routine imaging sequences, designed for anatomical quantification
flight simulator performance summary score
z-score composite of executing ATC communications, avoiding traffic, monitoring engine malfunctions, visual approach and landing
Time frame: yearly for up to 6 years
CogScreen-AE
computerized battery (assesses processing speed, executive function, paired assoc memory, n-back task, psychomotor tracking
Time frame: yearly
Salthouse processing speed measures
digit copy \& pattern comparison
Time frame: yearl
This study is completed, as verified in Feb 2017. You cannot join it, but the record below documents what was studied.
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Palo Alto Veterans Institute for Research