HISTOACRYL: A Study of Its Efficacy in Final Scar Formation

• Age: Younger than 21
• Gender: Females only. Given the nature of the procedures, as well as our clinical experience, we cannot anticipate recruiting enough male patients to be able to evaluate them as a subgroup. Since there may be differences in distributions of measures, to keep the groups more homogeneous we plan to recruit only females from the outset. Having either:

• Reduction Mammoplasty or mastopexy patients:

  • Patients who present to the plastic surgery clinic and are scheduled for breast procedures will be recruited and consented by a clinical studies co-ordinator.
  • This will include patients undergoing a standard Wise pattern reduction mammoplasty (reduction and lift) or a standard Wise pattern mastopexy (lift only). See exclusion criteria below.

• Abdominoplasty or panniculectomy patients:

  • Patients who present to the plastic surgery clinic and are scheduled for abdominal procedures will be recruited and consented by a clinical studies coordinator. See exclusion criteria below.

Exclusion Criteria:

• Though women of childbearing age will be allowed to participate in this study, no pregnant patients will be enrolled.

• Patients with any factors that may have an adverse effect on wound healing:

  • previous hypertrophic scars or keloid
  • known vitamin C deficiency
  • known zinc deficiency
  • smoking
  • steroid use
  • known connective tissue disorder
  • hypoalbuminemia
  • any factor not listed that the attending consultant seeing the patient feels would adversely effect wound healing.
• Patients who have a known sensitivity to adhesives