An observational study in Hypotension and Shock, sponsored by Hospital del SAS de Jerez. Completed at 1 site in Spain. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2009-04-29.
Sponsored by Hospital del SAS de Jerez · Observational
The investigators designed this study to determine the predictive value for predicting fluid responsiveness of noninvasive evaluation of respiratory variation of peak velocity in brachial artery, in mechanically ventilated patients with acute circulatory failure.
Predicting the hemodynamic response to fluid administration (or fluid responsiveness) in critical ill patients is still a matter of concern, since fluid overload could worse the clinical situation of these patients. Parameters of fluid responsiveness usually require an invasive monitoring (like arterial pulse pressure variation).
We hypothesize that noninvasive evaluation of respiratory variation of peak velocity in brachial artery using Doppler ultrasound could provide a feasible estimation on fluid responsiveness in mechanically ventilated patients with acute circulatory failure.
1,021 studies on the registry are indexed under Hypotension; 172 are open to participants now.
This study's enrollment of 38 is below the median of 84 across 301 observational studies indexed under Hypotension.
Browse Hypotension studies →Hospital del SAS de Jerez is the lead sponsor of 2 studies on the registry; none are open to participants now.
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Critical ill patients with controlled mechanical ventilation and acute circulatory failure.
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Patients with controlled mechanical ventilation, equipped with an indwelling radial artery catheter and for whom the decision to give fluids will be taken because the presence of one or more clinical signs of acute circulatory failure:
Exclusion Criteria:
Patients for whom the decision to give fluids was taken because the presence of one or more clinical signs of acute circulatory failure.
Other: Fluid administration
500 ml of synthetic colloid (Voluven®, hydroxyethylstarch 6%; Fresenius, Bad Homburg, Germany) infused over 30 minutes
Predictive value of respiratory variation in brachial artery peak velocity before volume expansion assessed by ROC curve. We defined responser as patients that increased stroke volume index equal or more than 15% after fluid administration.
Time frame: immediately after volume expansion
Evaluate the predictive value of pulse pressure variation for predicting hemodynamic response to fluid administration, comparing with the predictive value of respiratory variation of brachial artery peak velocity.
Time frame: immediately after fluid administration
Evaluate the predictive value of stroke volume variation for predicting hemodynamic response to fluid administration, comparing with the predictive value of respiratory variation of brachial artery peak velocity.
Time frame: immediately after volume expansion
This study is completed, as verified in Apr 2009. You cannot join it, but the record below documents what was studied.
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Hospital del SAS de Jerez