An observational study in Skin Cancer, sponsored by Ruhr University of Bochum. Completed at 1 site in Germany. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2012-10-16.
Sponsored by Ruhr University of Bochum · Observational
MicroRNAs (miRNAs) are very small endogenous RNA molecules about 22-25 nucleotides in length, capable of post-transcriptional gene regulation. miRNAs bind to their target messenger RNAs (mRNAs), leading to cleavage or suppression of target mRNA translation based on the degree of complementarity. miRNAs have recently been shown to play pivotal roles in diverse developmental and cellular processes and linked to a variety of skin diseases and cancers. In the present study the expression profiles for the two most important miRNA processing enzymes Dicer and Drosha of actinic keratoses, basal cell carcinoma and squamous cell carcinoma are compared to healthy skin tissue.
582 studies on the registry are indexed under Skin Neoplasms; 114 are open to participants now.
This study's enrollment of 28 is below the median of 200 across 134 observational studies indexed under Skin Neoplasms.
Browse Skin Neoplasms studies →Ruhr University of Bochum is the lead sponsor of 124 studies on the registry; 3 are open to participants now.
Counted across the registry records on this site, refreshed daily.
dermatologic primary care clinic
Exclusion Criteria:
Patients with actinic keratoses of the skin
Patients with basal cell carcinoma of the skin
Patients with squamous cell carcinoma of the skin
This study is completed, as verified in Oct 2012. You cannot join it, but the record below documents what was studied.
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Ruhr University of Bochum