An interventional study of Biopsy and sample of blood and Biopsy and sample of blood in Atopic Dermatitis, Contact Dermatitis and Psoriasis, sponsored by Assistance Publique Hopitaux De Marseille. Completed at 1 site in France. Open to participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2014-08-29.
Sponsored by Assistance Publique Hopitaux De Marseille · Not applicable and Interventional
Natural Killer (NK) cells play a unique role during innate immune responses as they are able to recognize and eliminate, without specific sensitization, tumors, microbe-infected cells as well as allogeneic cells.In a first time, we will characterize the tissue distribution, the phenotype and the effector functions of NK cells present in the human healthy skin.
Then, we will define whether these parameters are qualitatively/ quantitatively modified in the following skin pathologies: a) atopic dermatitis; b) contact dermatitis; c) psoriasis ; d) lichen planus ; e) GVH (graft versus host disease) ; (f) melanoma.
1,899 studies on the registry are indexed under Psoriasis; 233 are open to participants now.
This study's enrollment of 28 is below the median of 70 across 1,447 interventional studies indexed under Psoriasis.
Browse Psoriasis studies →Assistance Publique Hopitaux De Marseille is the lead sponsor of 686 studies on the registry; 148 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Healthy volunteer
Other: Biopsy and sample of blood
atopic dermatitis patient
Other: Biopsy and sample of blood
contact dermatitis patient
Other: Biopsy and sample of blood
psoriasis patient
Other: Biopsy and sample of blood
lichen planus patient
Other: Biopsy and sample of blood
GVH patient
Other: Biopsy and sample of blood
melanoma patient
Other: Biopsy and sample of blood
Biopsy and sample of blood
Biopsy and sample of blood
Biopsy and sample of blood
Biopsy and sample of blood
Biopsy and sample of blood
Biopsy and sample of blood
Biopsy and sample of blood
In a first time, we will characterize the tissue distribution, the phenotype and the effector functions of NK cells present in the human healthy skin.
Time frame: 12 months
To determine whether the eventual modifications detected in skin pathologies are correlated to qualitative/ quantitative alterations of NK cell subsets present in the peripheral blood.
Time frame: 12 months
This study is completed, as verified in Aug 2014. You cannot join it, but the record below documents what was studied.
Get an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.
Assistance Publique Hopitaux De Marseille