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CompletedNCT00812162Updated Jan 17, 2013

Effects of Dietary Pork and Egg on Appetite, Meal-patterning, and Weight Loss in Men

An interventional study of Energy Restriction and Energy Restriction in Weight Loss, sponsored by Purdue University. Completed at 1 site in United States. Open to male participants aged 21 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2013-01-17.

Sponsored by Purdue University · Not applicable, Interventional, and Prevention

Phase
Not applicable
Study type
Interventional
Enrollment
48
Allocation
Randomized
Ages
21 Years and older
Sex
Male
01

Study summary

The purpose of this study is to identify how adult men respond to a weight loss diet that includes pork and eggs and increasing the number of meals consumed throughout the day. This is a 13-week study (12-weeks of weight loss and 1-week of baseline measurement).

02

Conditions studied

  • Weight Loss
03

In context

Body Weight

1,223 studies on the registry are indexed under Body Weight; 132 are open to participants now.

This study's enrollment of 48 is below the median of 64 across 947 interventional studies indexed under Body Weight.

Browse Body Weight studies →

Lead sponsor

Purdue University is the lead sponsor of 168 studies on the registry; 23 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
21 Years and older
Sexes eligible
Male
Accepts healthy volunteers
Yes

Inclusion criteria

  • Age range: 21 years and older
  • Body mass index between 25.0-39.9 kg/m2
  • Weight stable (\< 4.5 kg (\~10 lbs) weight gain or loss within last 6 months)
  • Body fat >25% (assessed by skinfold and plethysmography (if needed))
  • Non-smoking (within the last 6 months)
  • Constant habitual activity patterns (within last 3 months)
  • Clinically normal blood profiles (specifically, normal liver and kidney function; fasting blood glucose \<110 mg/dl)
  • Not taking medications known to influence appetite or metabolism
  • Non-diabetic

Exclusion criteria

Exclusion Criteria:

  • Age: \<21 years
  • Body mass index: outside of the 25.0-39.9 kg/m2 range
  • Gained or lost > 4.5 kg (10 lbs) within the last 6 months
  • Body fat \<25% as assessed by plethysmography
  • Smoker (currently or within the last 6 months)
  • Intermittently been involved in a diet and/or exercise program within the last 3 months
  • Clinically abnormal blood profiles as identified by our study physician, Arthur Rosen, MD
  • Taking medications (currently or within the last 3 months) known to influence appetite or metabolism
  • Clinically diagnosed as diabetic
  • Allergies to eggs
  • Lactose intolerance
  • Clinically diagnosed with diverticulosis
  • Clinically diagnosed with diverticulitis
05

Study design

Phase
Not applicable
Primary purpose
Prevention
Allocation
Randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
48 participants (actual)

Study arms

  • Experimental
    1

    High protein diet.

    Other: Energy Restriction

  • Experimental
    2

    Lower protein diet.

    Other: Energy Restriction

Interventions

  • OtherEnergy Restriction

    Energy restricted diet of 750 kcal less than subjects requirement with a high protein diet.

  • OtherEnergy Restriction

    Energy restricted diet of 750 kcal less than subjects requirement with a lower protein diet.

06

What researchers measure

Primary outcomes

  1. The primary aim is to examine the effects of increased protein intake on appetite, selected appetite hormones (insulin, leptin, ghrelin), whole body energy expenditure, and body composition (fat mass and fat-free mass) changes.

    Time frame: 12 week

Secondary outcomes

  1. The secondary aim of this study is to evaluate the effects of meal frequency on appetite by asking the men to frequently rate their appetite on days that they purposefully eat 3 vs. 6 times/day.

    Time frame: 12 week

07

Study locations

1 site
  • Purdue University
    West Lafayette, Indiana 47907, United States
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jan 17, 2013, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT00812162
Lead sponsor
Purdue University
Responsible party
Wayne Campbell (Wayne Campbell, Ph.D., Purdue University) — Principal investigator
First posted
Dec 22, 2008
Start date
Jan 2007
Primary completion
Feb 2009
Completion
Jul 2011
Last update
Jan 17, 2013

Study contacts

Wayne W Campbell, Ph.D.
principal investigator · Purdue University

Oversight

Data monitoring committee
Yes
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Jan 2013. You cannot join it, but the record below documents what was studied.

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