An interventional study of Dental Implant (Nanotite) in Tooth Disease and Partial Edentulism, sponsored by ZimVie. Completed at 1 site in Spain. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-07-28.
Sponsored by ZimVie · Not applicable, Interventional, and Treatment
This prospective randomized study will evaluate the integration success while supporting a prosthesis for short implants placed into maxillary sites having minimal bone height that would otherwise need sinus augmentation. The resources utilized during treatment will be assessed.
Study (null) hypothesis: the overall benefit of using short length implants to avoid sinus augmentation procedures will offset differences in the cumulative implant survival rates observed between treatment groups.
In this randomized study, patients needing restorations in the posterior maxilla will be randomly assigned to the short implant group (test) or the standard length and augmentation group (control). All implants will be placed using a two-stage approach with healing abutments placed at three months and temporary prosthesis at four months following implant and/ or sinus augmentation surgery. Time, materials, and efforts associated with treating test and control cases will be documented to allow an assessment of the costs incurred with each approach.
79 studies on the registry are indexed under Tooth Diseases; 11 are open to participants now.
This study's enrollment of 37 is below the median of 49 across 63 interventional studies indexed under Tooth Diseases.
Browse Tooth Diseases studies →ZimVie is the lead sponsor of 24 studies on the registry; 2 are open to participants now.
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Exclusion Criteria:
Dental implants of short length placed without sinus lifts
Device: Dental Implant (Nanotite)
Dental implants of standard length placed simultaneously with sinus augmentation
Root form titanium dental implant
Also known as: Nanotite
Integration Success of Implant
Number of enrolled and treated patients with integrated implants (no mobility detected) at time of analysis.
Time frame: 3 years
Patients enrolled in the study according to inclusion/ exclusion criteria as described in the protocol. Patient enrollment began February 2009 and ended February 2011. All study patients were enrolled at 3 European Universities (dental clinics).
| Milestone | Dental Implant (Nanotite) | Control Group |
|---|---|---|
| Started | 17 | 20 |
| Completed | 17 | 20 |
| Not completed | 0 | 0 |
Number of enrolled and treated patients with integrated implants (no mobility detected) at time of analysis.
| participants | Dental Implant (Nanotite) | Control Group |
|---|---|---|
| Integration Success of Implant | 17 | 20 |
Collected over Adverse events are collected and reported from day 1 of the study to present time (entire duration of study).. Non-serious events are listed at a 5% frequency threshold.
| Group | Deaths | Serious | Other |
|---|---|---|---|
| Dental Implant (Nanotite) | — | 0/17 (0%) | 6/17 (35.3%) |
| Control Group | — | 0/20 (0%) | 5/20 (25%) |
| Event | Dental Implant (Nanotite) | Control Group |
|---|---|---|
| MobilitySurgical and medical procedures | 6/17 | 5/20 |
| Age, Categorical(Participants) | Dental Implant (Nanotite) | Control Group | Total |
|---|---|---|---|
| <=18 years | 0 | 0 | 0 |
| Between 18 and 65 years | 14 | 18 | 32 |
| >=65 years | 3 | 2 | 5 |
| Sex: Female, Male(Participants) | Dental Implant (Nanotite) | Control Group | Total |
|---|---|---|---|
| Female | 6 | 12 | 18 |
| Male | 11 | 8 | 19 |
| Region of Enrollment(participants) | Dental Implant (Nanotite) | Control Group | Total |
|---|---|---|---|
| Spain | 5 | 4 | 9 |
| Greece | 3 | 6 | 9 |
| Italy | 9 | 10 | 19 |
Plan to share: No
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This study is completed, as verified in Mar 2022. You cannot join it, but the record below documents what was studied.
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