An interventional study of Eztetic dental implant in Edentulous Jaw, sponsored by ZimVie. Completed at 4 sites in 3 countries. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-08-12.
Sponsored by ZimVie · Not applicable, Interventional, and Treatment
This will be a prospective, observational multicenter study. All implants will be placed in the anterior maxilla or mandible and immediately loaded with a provisional prosthesis out of occlusion. Final restorations insertion will take place no later than 6 months following implant placement surgery. All implants will be restored with a single crown or splinted to a pre-existing implant if in the pre-molar region (no 2 adjacent edentulous sites).
This will be a prospective, observational study in which patients in need of dental implants in the anterior regions of the maxilla or mandible will be treated with the Eztetic dental implant(s). Qualified patients will be those with one or more edentulous area in the anterior maxilla or mandible needing a single (restored as a single crown; if in the pre-molar region, it is recommended implant be splinted to another tooth or implant; no 2 adjacent edentulous sites). Qualified patients should have presence of posterior teeth or a stable posterior occlusion. All implants will be placed in a single-stage manner. A provisional abutment will be placed and a temporary crown will be placed (cemented or screw-retained) out of occlusion at implant placement surgery visit. Impressions for permanent prosthesis fabrication will take place at 6 weeks and prosthesis placement will take place at 2 months. Final prosthesis insertion will take place no later than 6 months following implant placement surgery. Resonance frequency assessment procedures will be done at implant placement surgery and at prosthesis insertion. Implant survival will be the primary study endpoint. Crestal bone regression will be the secondary study endpoint. Enrollment will continue until 20 patients have completed final prosthetic treatment at study center.
122 studies on the registry are indexed under Jaw, Edentulous; 20 are open to participants now.
This study's enrollment of 82 is above the median of 24 across 99 interventional studies indexed under Jaw, Edentulous.
Browse Jaw, Edentulous studies →ZimVie is the lead sponsor of 24 studies on the registry; 2 are open to participants now.
Counted across the registry records on this site, refreshed daily.
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Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
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You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Anti-inflammatory medicines such as prednisone, prednisolone and dexamethasone — not the anabolic steroids used for muscle.
Studies differ in what they allow: check which steroid medicines, routes (tablets, injections, creams, inhalers, eye drops) and doses this study accepts.
The human immunodeficiency virus, which weakens the immune system.
Many studies now accept people whose HIV is controlled on treatment, judged by the viral load and the CD4 count. Check the limits this study sets.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Corticosteroids (steroids)
Anti-inflammatory medicines such as prednisone, prednisolone and dexamethasone — not the anabolic steroids used for muscle.
Studies differ in what they allow: check which steroid medicines, routes (tablets, injections, creams, inhalers, eye drops) and doses this study accepts.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
HIV
The human immunodeficiency virus, which weakens the immune system.
Many studies now accept people whose HIV is controlled on treatment, judged by the viral load and the CD4 count. Check the limits this study sets.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Eztetic 3.1mm diameter, lengths 8, 10, 11.5, 13, 16 mm
Device: Eztetic dental implant
narrow diameter dental implant
Number of Implants Surviving up to 2 Years
survival (no declaration of failure) of dental implant
Time frame: 2 years
Marginal Crestal Bone Changes up to 2 Years
Average change in bone levels around dental implant at 2 years as compared to that of baseline (time of implant placement)
Time frame: 2 years
| Milestone | Eztetic Dental Implant |
|---|---|
| Started | 82 |
| Completed | 55 |
| Not completed | 27 |
survival (no declaration of failure) of dental implant
| implants | Eztetic Dental Implant |
|---|---|
| Number of Implants Surviving up to 2 Years | 58 |
Average change in bone levels around dental implant at 2 years as compared to that of baseline (time of implant placement)
| millimeters | Eztetic Dental Implant |
|---|---|
| Marginal Crestal Bone Changes up to 2 Years | 0.19 ± 0.4 |
Collected over from enrollment until the end of 2 year follow up. Non-serious events are listed at a 0% frequency threshold.
| Group | Deaths | Serious | Other |
|---|---|---|---|
| Eztetic Dental Implant | 0/82 (0%) | 0/82 (0%) | 4/82 (4.9%) |
| Event | Eztetic Dental Implant |
|---|---|
| implant failureSurgical and medical procedures | 4/82 |
| Age, Categorical(Participants) | Eztetic Dental Implant |
|---|---|
| <=18 years | 0 |
| Between 18 and 65 years | 75 |
| >=65 years | 7 |
| Sex: Female, Male(Participants) | Eztetic Dental Implant |
|---|---|
| Female | 57 |
| Male | 25 |
| Race (NIH/OMB)(Participants) | Eztetic Dental Implant |
|---|---|
| American Indian or Alaska Native | 0 |
| Asian | 0 |
| Native Hawaiian or Other Pacific Islander | 3 |
| Black or African American | 5 |
| White | 74 |
| More than one race | 0 |
| Unknown or Not Reported | 0 |
PDFs hosted by the registry, ClinicalTrials.gov.
Plan to share: No
Ran from Jan 2019 to primary completion in May 2023, 52 months.
Results were first posted in Aug 2026, 3 years 2 months after primary completion.
Of 66 interventional studies with no phase under Jaw, Edentulous, half reached primary completion within 20 months of starting (the median), counting those still running; a quarter within 12 and three quarters within 38. This study's 52 months is above that.
How these figures are worked out, and which studies are left out of them.
This study is completed, as verified in Jul 2026. You cannot join it, but the record below documents what was studied.
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