An observational study in Partial Edentulism, sponsored by ZimVie. Completed at 1 site in Austria. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-09-08.
Sponsored by ZimVie · Observational
This observational, prospective clinical study evaluates the performance of the Certain Prevail implant system to show potential crestal bone and soft tissue preservation following the crestal bone. It will also evaluate implant performance.
Study (null) hypothesis: The preservation of crestal bone for the Certain Prevail implants will be the same as that for standard non-platform switched implants from contemporaneous studies (historical controls).
This is a prospective, observational study of patients with partial or complete edentulism treated with the Certain Prevail dental implants. Restorations will consist of single tooth replacements, short and long fixed bridges, and overdentures and full dentures. All implants are placed using a single stage approach and temporalization occurring after two months of healing (early loading). Each center will strive to enroll a total of 20 patients.
ZimVie is the lead sponsor of 24 studies on the registry; 2 are open to participants now.
Counted across the registry records on this site, refreshed daily.
These will be patients who are otherwise seeking dental implant therapy and belong to the study centers' standard patient population.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
patients for whom a decision has already been made to use dental implants for treating an existing dental condition specifically:
Exclusion Criteria:
Osseous Integration
Time frame: 2 years
161 patients were enrolled across all participating centers, with enrollment efforts beginning in September 6 2005 (first patient enrolled) and completing in January 22 2007 (last patient enrolled). Ten participating sites are private practices and two are Universities.
| Milestone | Certain Prevail Implants |
|---|---|
| Started | 161 |
| Completed | 161 |
| Not completed | 0 |
| Milestone | Certain Prevail Implants |
|---|---|
| Started | 161 |
| Completed | 49 |
| Not completed | 112 |
| Withdrew: Lost to follow-up | 112 |
| participants | Certain Prevail Implants |
|---|---|
| Osseous Integration | 145 |
Collected over Adverse event reports are collected from implant placement surgery until final follow up visit, 2 year. Non-serious events are listed at a 1% frequency threshold.
| Group | Deaths | Serious | Other |
|---|---|---|---|
| Certain Prevail Implants | 0/161 (0%) | 0/161 (0%) | 7/161 (4.3%) |
| Event | Certain Prevail Implants |
|---|---|
| implant failureMusculoskeletal and connective tissue disorders | 7/161 |
| Age, Categorical(Participants) | Certain Prevail Implants |
|---|---|
| <=18 years | 0 |
| Between 18 and 65 years | 135 |
| >=65 years | 27 |
| Sex: Female, Male(Participants) | Certain Prevail Implants |
|---|---|
| Female | 99 |
| Male | 63 |
| Region of Enrollment(Participants) | Certain Prevail Implants |
|---|---|
| Austria | 26 |
| Australia | 10 |
| Ireland | 14 |
| United States | 31 |
| Italy | 52 |
| France | 9 |
| Sweden | 20 |
PDFs hosted by the registry, ClinicalTrials.gov.
Plan to share: No
This study is completed, as verified in Jul 2026. You cannot join it, but the record below documents what was studied.
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