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CompletedNCT00641069Updated Jul 15, 2009

Automated Chest Compression in Cardiac Arrest

An observational study in Cardiac Arrest, sponsored by Beaujon Hospital. Completed at 1 site in France. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2009-07-15.

Sponsored by Beaujon Hospital · Observational

Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
30
Ages
18 Years and older
Sex
All
01

Study summary

To evaluate the effect of use of automated chest compression device on blood pressure in patients presenting with cardiac arrest. Higher systolic, diastolic and mean blood pressures are expected.

Read the detailed description

The protocol compares arterial pressures produced by an automated self-adjusting load-distributing band device (AutoPulse™ 100, Zoll®) with those of manual cardiopulmonary resuscitation in refractory out-of-hospital cardiac arrest. Each patient will receive first manual compressions and then automated resuscitation.

Patients presenting with cardiac arrest are treated following standard advanced life support guidelines. They are intubated and ventilated, received epinephrine and defibrillation if appropriate. Manuel chest compressions are continued. An arterial catheter is placed to monitor hemodynamics continuously as we usually do in this case. Patients are included at this stage. Three blood pressure values (every 1 minutes) are recorded. Then, the automated band device is started up without any pause, following our procedure for refractory cardiac arrest. Three blood pressure values are recorded again, during automated cardiopulmonary resuscitation.

02

Conditions studied

  • Cardiac Arrest

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Keywords

  • Cardiac arrest
  • Cardiopulmonary resuscitation
03

In context

Heart Arrest

965 studies on the registry are indexed under Heart Arrest; 226 are open to participants now.

This study's planned enrollment of 30 is below the median of 200 across 382 observational studies indexed under Heart Arrest.

Browse Heart Arrest studies →

Lead sponsor

Beaujon Hospital is the lead sponsor of 10 studies on the registry; none are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Probability sample

Study population

Patients aged > 18 with out-of-hospital cardiac arrest

Inclusion criteria

  • Age ≥ 18
  • Refractory cardiac arrest

Exclusion criteria

Exclusion Criteria:

  • Defective invasive arterial blood pressure monitoring
05

Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
30 participants (estimated)

Interventions

  • DeviceAutomated load-distributing band device

    Blood pressure recording before and after starting up the automated band device

    Also known as: AutoPulse™ 100, Zoll®

06

What researchers measure

Primary outcomes

  1. Diastolic blood pressures produced by manual and then by automated chest compressions will be recorded for each patient

    Time frame: Instantaneously

Secondary outcomes

  1. Systolic blood pressures produced by manual and then by automated chest compressions will be recorded for each patient

    Time frame: Instantaneously

  2. Mean blood pressures produced by manual and then by automated chest compressions will be recorded for each patient

    Time frame: Instantaneously

07

Study locations

1 site
  • Departement of Anesthesiology, Intensive Care and EMS, Beaujon University Hospital
    Clichy, 92110, France
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jul 15, 2009, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT00641069
Lead sponsor
Beaujon Hospital
First posted
Mar 21, 2008
Start date
Feb 2008
Primary completion
Jan 2009
Completion
Jan 2009
Last update
Jul 15, 2009

Study contacts

Francois-Xavier Duchateau, MD
principal investigator · Departement of Anesthesiology, Intensive Care and EMS, Beaujon University Hospital
Jean Mantz, MDPhD
study chair · Departement of Anesthesiology, Intensive Care and EMS, Beaujon University Hospital

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Jul 2009. You cannot join it, but the record below documents what was studied.

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