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TerminatedNCT00599820Updated Jun 3, 2024

Use of Intravitreal Bevacizumab in Eyes With Choroidal Neovascularization Secondary to Angioid Streaks

A Phase 3 interventional study of Intravitreal Bevacizumab in Angioid Streaks and Choroidal Neovascularization, sponsored by Asociación para Evitar la Ceguera en México. Terminated at 1 site in Mexico. Per ClinicalTrials.gov, last updated 2024-06-03.

Sponsored by Asociación para Evitar la Ceguera en México · Phase 3, Interventional, and Treatment

Why this study was terminated
Poor accrual

From the registry’s dates

  • Registered 7 months after the study started (first participant enrolled Nov 2005, registered Jun 2006).
Phase
Phase 3
Study type
Interventional
Allocation
Non-randomized
Sex
All
01

Where this study stands

Counted across the records on this site · 2026-11-12

Among 14 studies testing bevacizumab in Choroidal Neovascularization — none open to participants now, none under way, none of them phase 3. Bevacizumab · Choroidal Neovascularization.

Started
2005
with 3 others
Phase 3
6 of 14
none open now
Registered
2nd of 14
by date
Lead sponsor
3 of 14
Asociación para Evitar la Ceguera en México

Among the 14 studies testing bevacizumab in Choroidal Neovascularization, this one is one of 4 that started in 2005, is one of 6 in phase 3, and was the 2nd registered.

By phase

14 studies; the count open now beside each. This study's row is marked.

Phase 3this study6 · 0 open
No phase3 · 0 open
Phase 23 · 0 open
Phase 11 · 0 open
Phase 2/31 · 0 open

By the year they started

First in 2005; this study’s year is marked. 4 started in 2005.

Tested beside bevacizumab

Size and results

Median enrollment 25 across the 12 interventional studies. Of the 10 that completed or were terminated, 2 (20%) have results posted.

Download CSVWith an account: the 14 studies testing bevacizumab in Choroidal Neovascularization as a file.
02

Study summary

Intravitreal Bevacizumab is an effective treatment for choroidal neovascularization secondary to Angioid Streaks

Read the detailed description

A consecutive case series of patients with angioid streaks that developed subfoveal choroidal neovascularization were treated with a primary 2.5 mg injection of Bevacizumab (Avastin) intravitreally. All patients were evaluated with BCVA at 1, 2 , 4 and 12 weeks and OCT and fluoresceine angiography at month 1 and 3. (Patients will be follow 6 months)

03

Conditions studied

  • Angioid Streaks
  • Choroidal Neovascularization

Keywords

  • Angioid Streaks
  • Choroidal Neovascularization
  • Bevacizumab
04

Who can participate

Ages eligible
Child (0–17), Adult (18–64), Older adult (65+)
Sexes eligible
All
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Clinical diagnosis of Angioid Streaks
  • Choroidal neovascularization associated
  • Untreated patients or patients treated once with PDT

Exclusion criteria

Exclusion Criteria:

  • Ocular surgery excepting uncomplicated phacoemulsification
  • Glaucoma or any other ocular pathology
05

Study design

Phase
Phase 3
Primary purpose
Treatment
Allocation
Non-randomized
Intervention model
Single group
Masking
None (open label)

Interventions

06

What researchers measure

Primary outcomes

  1. BCVA

  2. Fluoresceine Angiography

  3. Optical Coherence Tomography

07

Study locations

1 site
  • Asociación para Evitar la Ceguera en México (APEC)
    México city, Distrito Federal 04030, Mexico
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jun 3, 2024, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT00599820
Lead sponsor
Asociación para Evitar la Ceguera en México
First posted
Jan 24, 2008
Start date
Nov 2005
Primary completion
Nov 2005
Completion
May 2006
Last update
Jun 3, 2024

Study contacts

Adriana Solís-Vivanco, MD
principal investigator · Asociación para Evitar la Ceguera en México
Jans Fromow-Guerra, MD PhD
study chair · Asociación para Evitar la Ceguera en México
Mariana Martínez-Castellanos, MD
study chair · Asociación para Evitar la Ceguera en México
Elizabeth Reyna-Castelán, MD
study chair · Asociación para Evitar la Ceguera en México
Myriam Hernández-Rojas, MD
study chair · Asociación para Evitar la Ceguera en México
Griselda Alvarez-Rivera, MD
study chair · Asociación para Evitar la Ceguera en México
Hugo Quiroz-Mercado, MD
study director · Asociación para Evitar la Ceguera en México
View the source record on ClinicalTrials.gov ↗

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This study is terminated, as verified in May 2024. You cannot join it, but the record below documents what was studied.

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