CClinicalTrials.gg
CompletedNCT00559832Updated Nov 16, 2007

Prevention of Acute Mountain Sickness by Intermittent Hypoxia

An interventional study of Hypoxic Exposure in Acute Mountain Sickness, sponsored by Heidelberg University. Completed at 1 site in Germany. Open to male participants aged 18 Years to 50 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2007-11-16.

Sponsored by Heidelberg University · Not applicable, Interventional, and Prevention

Phase
Not applicable
Study type
Interventional
Enrollment
75
Allocation
Randomized
Ages
18 Years to 50 Years
Sex
Male
01

Study summary

Acclimatization by mountaineering prior to high altitude sojourns have shown to be effective in prevention of acute mountain sickness (AMS).

The aim of this study is to investigate whether intermittent exposure to normobaric hypoxia during sleep is also effective to prevent AMS.

02

Conditions studied

  • Acute Mountain Sickness

Keywords

  • acute mountain sickness
  • intermittent hypoxia
  • acclimatization
03

In context

Altitude Sickness

189 studies on the registry are indexed under Altitude Sickness; 44 are open to participants now.

This study's enrollment of 75 is above the median of 33 across 157 interventional studies indexed under Altitude Sickness.

Browse Altitude Sickness studies →

Lead sponsor

Heidelberg University is the lead sponsor of 279 studies on the registry; 17 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 50 Years
Sexes eligible
Male
Accepts healthy volunteers
Yes

Inclusion criteria

  • healthy

Exclusion criteria

Exclusion Criteria:

  • Altitude exposure above 2000 m 8 weeks prior or during the study
05

Study design

Phase
Not applicable
Primary purpose
Prevention
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Double
Enrollment
75 participants (actual)

Study arms

  • No intervention
    Normoxia

    Sleeping in normoxia for 14 nights prior to one night at 4500 m

  • Experimental
    Hypoxia

    Sleeping in normobaric hypoxia for 14 nights at altitudes from 2500 - 3300 m prior to one night at 4500 m

    Other: Hypoxic Exposure

Interventions

  • OtherHypoxic Exposure

    Sleeping in normobaric hypoxia for 14 nights at altitudes from 2500 - 3300 m prior to one night at 4500 m

06

What researchers measure

Primary outcomes

  1. incidence of acute mountain sickness

    Time frame: during one night at 4500 m

Secondary outcomes

  1. Sleep quality

    Time frame: during one night at altitude

  2. ventilatory acclimatization

    Time frame: during one night at altitude

07

Study locations

1 site
  • Sports Medicine, University Hospital
    Heidelberg, 69120, Germany
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Nov 16, 2007, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT00559832
Lead sponsor
Heidelberg University
First posted
Nov 16, 2007
Start date
Mar 2006
Completion
Jul 2007
Last update
Nov 16, 2007

Study contacts

Christoph Dehnert, MD
principal investigator · University Hospital Heidelberg

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Nov 2007. You cannot join it, but the record below documents what was studied.

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