An interventional study of Hydrogel dressing and Lacrilube ointment in Keratitis, sponsored by Barts & The London NHS Trust. Completed. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2007-08-09.
Sponsored by Barts & The London NHS Trust · Not applicable, Interventional, and Prevention
Corneal damage in critically ill patients is common. There are currently two popular methods of treatment in the UK; hydrogel dressings and lubricating ointment. We propose to randomise patients to have a different treatment for each eye and see which one is more effective.
Microbial keratitis, particularly pseudomonas-related, has been widely reported amongst Intensive therapy unit (ITU) patients and the need for effective eye care in ITU has been recognised for some time. We compare two popular methods of eye care; a hydrogel dressing and lacrilube ointment. Each recruited patient had each eye randomised to different treatments. Daily ophthalmology ward rounds were undertaken to identify any corneal exposure keratopathy. Patients were removed from the trial if one eye developed significant exposure needing treatment.
126 studies on the registry are indexed under Keratitis; 15 are open to participants now.
This study's enrollment of 40 is above the median of 36 across 79 interventional studies indexed under Keratitis.
Browse Keratitis studies →Barts & The London NHS Trust is the lead sponsor of 149 studies on the registry; 21 are open to participants now.
Of its 5 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.
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Exclusion Criteria:
Geliperm Hydrogel Dressing
Other: Hydrogel dressing
Lacrilube ointment
Other: Lacrilube ointment
3x3cm hydrogel dressing over closed eye
lubricant put into eye (inferior formix)
Development of clinically significant corneal exposure
Time frame: throughout length of admission to ITU
No study locations are listed for this record.
This study is completed, as verified in Aug 2007. You cannot join it, but the record below documents what was studied.
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Barts & The London NHS Trust