An interventional study of glucontrol (insulin therapy) in the Maintenance of Normoglycemia, the Incidence of Ventilator Associated Pneumonia (VAP) and Treatment Period in the Intensive Care Unit, sponsored by University Medical Centre Ljubljana. Completed at 1 site in Slovenia. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2008-10-24.
Sponsored by University Medical Centre Ljubljana · Not applicable, Interventional, and Prevention
Aim. To determine whether the maintenance of normoglycemia decreases the incidence of ventilator associated pneumonia (VAP), reduces its treatment period and the length of stay in the intensive care unit.
Methods. Prospective, randomized, controlled trial. We enrolled 117 mechanically ventilated trauma (71) and abdominal (46) surgical patients, older than 18, of both sex. In 57 patients (strict glucose control group) we aimed to maintain the blood glucose level between 4.4 and 6. 1 mmol/L, while in 60 patients (standard glucose control group) it was maintained between 7.8 and 10.0 mmol/L, with the use of continues insulin infusion. Insulin dose adjustments were based on measurements of glucose in capillary blood sample.
Key words: surgical patients; mechanical ventilation; pneumonia; blood glucose; insulin infusion; hospital stay
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2,044 studies on the registry are indexed under Pneumonia; 283 are open to participants now.
This study's enrollment of 117 is above the median of 106 across 1,247 interventional studies indexed under Pneumonia.
Browse Pneumonia studies →University Medical Centre Ljubljana is the lead sponsor of 284 studies on the registry; 71 are open to participants now.
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Exclusion Criteria:
measurements of glucose in capillary blood sample
This study is completed, as verified in Mar 2007. You cannot join it, but the record below documents what was studied.
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University Medical Centre Ljubljana