An interventional study of timolol maleate 0,5% and brimonidine tartrate 0,2% in Glaucoma, sponsored by University of Sao Paulo. Completed. Open to participants aged 18 Years to 80 Years. Per ClinicalTrials.gov, last updated 2007-02-19.
Sponsored by University of Sao Paulo · Not applicable, Interventional, and Treatment
During the glaucomatous disease process, subpopulations of cells may be dead, damaged or healthy. Visual function changes could be observed due to a recovering of the suffering ganglion cells after the intraocular pressure reduction. This study aims at evaluating the correlation between intraocular pressure reduction and visual function changes in glaucoma patients after using antiglaucoma medications.
Primary open angle glaucoma patients without use of antiglaucoma medications will be enrolled in this study. After inclusion, the patients will randomly receive one of three antiglaucoma medications (timolol maleate 0,5%, brimonidine tartrate 0,2% or travoprost 0,004%) in one randomly selected eye.
The patients will be evaluated with Goldmann applanation tonometry, visual acuity test, contrast sensitivity test, visual quality perception test (visual analogue scale) and standard automated perimetry before and after 4 weeks of glaucoma treatment onset.
1,818 studies on the registry are indexed under Glaucoma; 231 are open to participants now.
This study's enrollment of 54 is below the median of 65 across 1,272 interventional studies indexed under Glaucoma.
Browse Glaucoma studies →University of Sao Paulo is the lead sponsor of 1,005 studies on the registry; 90 are open to participants now.
Of its 7 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.
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Exclusion Criteria:
intraocular pressure
contrast sensitivity
visual quality perception
Mean deviation of the visual field (MD)
Pattern Standard Deviation of the visual field (PSD)
visual acuity
No study locations are listed for this record.
This study is completed, as verified in Feb 2007. You cannot join it, but the record below documents what was studied.
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University of Sao Paulo