CClinicalTrials.gg
Status unknownNCT00430664Updated Feb 2, 2007

A Comparative Study of the Safety and Efficacy of Face Talc Slurry and Iodopovidone for Pleurodesis

An interventional study of Pleurodesis with either talc or iodopovidone in Malignant Pleural Effusions, Recurrent Pleural Effusions and Primary Spontaneous Pneumothorax, sponsored by Post Graduate Institute of Medical Education and Research, Chandigarh. Status unknown at 1 site in India. Open to participants aged 12 Years and older. Per ClinicalTrials.gov, last updated 2007-02-02.

Sponsored by Post Graduate Institute of Medical Education and Research, Chandigarh · Not applicable, Interventional, and Treatment

The sponsor has not verified this record recently (last verified Feb 2007), so the status shown — last known as Recruiting — may be out of date.
Phase
Not applicable
Study type
Interventional
Enrollment
100
Allocation
Randomized
Ages
12 Years and older
Sex
All
01

Study summary

Pleurodesis is a technique used to fuse the two layers of the lining over the lung. This is done to get rid of collections of fluid or air in this space. A common reason would be cancer of the underlying lung or elsewhere causing fluid to collect in the pleural space. In this situation it is a palliative procedure to free the patient from symptoms like breathlessness.

Read the detailed description

Pleurodesis is a technique used to fuse the two layers of the pleura. This is done to prevent reaccumulation of collections of fluid or air in this space. Common indications are malignant pleural effusions, recurrent pneumothorax and even benign effusions which are otherwise difficult to eradicate.

02

Conditions studied

  • Malignant Pleural Effusions
  • Recurrent Pleural Effusions
  • Primary Spontaneous Pneumothorax
  • Secondary Spontaneous Pneumothorax

Keywords

  • pleurodesis
  • talc
  • iodopovidone
03

In context

Pleural Effusion, Malignant

154 studies on the registry are indexed under Pleural Effusion, Malignant; 39 are open to participants now.

This study's enrollment of 100 is above the median of 57 across 112 interventional studies indexed under Pleural Effusion, Malignant.

Browse Pleural Effusion, Malignant studies →

Lead sponsor

Post Graduate Institute of Medical Education and Research, Chandigarh is the lead sponsor of 290 studies on the registry; 42 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
12 Years and older
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • Age over 12 years
  • Symptomatic recurrent pleural effusion
  • Pneumothorax needing pleurodesis

Exclusion criteria

Exclusion Criteria:

  • Life expectancy \<1 month
  • Unwilling to give consent
  • Empyema
  • ICTD drain output >150 ml/d
  • Presence of an airleak
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Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
100 participants

Interventions

  • ProcedurePleurodesis with either talc or iodopovidone
06

What researchers measure

Primary outcomes

  1. Success

  2. Failure

Secondary outcomes

  1. Death

  2. Pain by VAS

  3. Time to Pleurodesis

  4. Others

07

Study locations

1 of 1 sites recruiting
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Feb 2, 2007, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT00430664
Lead sponsor
Post Graduate Institute of Medical Education and Research, Chandigarh
First posted
Feb 2, 2007
Start date
Jan 2006
Completion
Dec 2007
Last update
Feb 2, 2007

Study contacts

Dheeraj Gupta, MD, DM, FCCP
principal investigator · Additional Professor, Dept of Pulmonary Medicine, PGIMER, Chandigarh, India
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in Feb 2007. You cannot join it, but the record below documents what was studied.

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