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TerminatedNCT00417833Updated Jun 3, 2024

Multifocal Electrophysiologic Findings After Intravitreal Bevacizumab(Avastin)Treatment

A Phase 2/3 interventional study of Intravitreal Bevacizumab in Diabetic Proliferative Retinopathy, Vascular Vein Oclussion and Choroidal Neovascularization, sponsored by Asociación para Evitar la Ceguera en México. Terminated. Per ClinicalTrials.gov, last updated 2024-06-03.

Sponsored by Asociación para Evitar la Ceguera en México · Phase 2/3 and Interventional

Why this study was terminated
Poor accrual
Phase
Phase 2/3
Study type
Interventional
Allocation
Non-randomized
Sex
All
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Study summary

Purpose: Determine the short-term safety of intravitreal bevacizumab by multifocal electroretinography (mf-ERG).

Methods: 120 eyes with choroidal neovascularization, proliferative diabetic retinopathy and retinal vein occlusion received intravitreal bevacizumab (2.5mg/0.1cc). All patients underwent best corrected visual acuity, fluorescein angiography, optical coherent tomography and mf-ERG before and 1 month after treatment.

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Conditions studied

  • Diabetic Proliferative Retinopathy
  • Vascular Vein Oclussion
  • Choroidal Neovascularization
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In context

Choroidal Neovascularization

214 studies on the registry are indexed under Choroidal Neovascularization; 12 are open to participants now.

Browse Choroidal Neovascularization studies →

Lead sponsor

Asociación para Evitar la Ceguera en México is the lead sponsor of 60 studies on the registry; 6 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
Child (0–17), Adult (18–64), Older adult (65+)
Sexes eligible
All

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Proliferative diabetic retinopathy, vascular vein oclussion, choroidal neovascularization
  • Multifocal electroretinogram before intravitreal bevacizumab and at 1,3, and 6 months after treatment
  • Completely studies

Exclusion criteria

Exclusion Criteria:

Complications

  • Tractional Detachment
  • Endophthalmitis
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Study design

Phase
Phase 2 / Phase 3
Allocation
Non-randomized
Intervention model
Single group
Masking
None (open label)

Interventions

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Study locations

No study locations are listed for this record.

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Timeline

Tracking since Sep 25, 2026
Not marked actual or estimatedDates not marked actual or estimated

The record gives a start of Dec 2005 and a completion of Jul 2006. It does not say whether these dates are actual or estimated.

How these figures are worked out, and which studies are left out of them.

Registered
Jan 3, 2007
First posted
Jan 4, 2007
Start
Dec 2005
Completion
Jul 2006
Last update
Jun 3, 2024
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
No changes since tracking began. The registry record was last updated on Jun 3, 2024, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT00417833
Lead sponsor
Asociación para Evitar la Ceguera en México
First posted
Jan 4, 2007
Start date
Dec 2005
Completion
Jul 2006
Last update
Jun 3, 2024

Study contacts

Myrian L Hernández, MD
principal investigator · Asociación para Evitar la Ceguera en México
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is terminated, as verified in May 2024. You cannot join it, but the record below documents what was studied.

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