ClinicalTrials.gg
CompletedNCT00354588Updated Nov 4, 2010

Arterial Stiffness, Wave Reflections and Renal Failure

An observational study in Chronic Renal Failure, Arterial Stiffness and Arterial Wave Reflections, sponsored by Klinikum Wels-Grieskirchen. Completed at 1 site in Austria. Open to participants aged 19 Years and older. Per ClinicalTrials.gov, last updated 2010-11-04.

Sponsored by Klinikum Wels-Grieskirchen · Observational

Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
115
Ages
19 Years and older
Sex
All
01

Study summary

  1. Cardiovascular risk is high in patients with renal failure.
  2. Cross-sectional studies have indicated a relationship between arterial stiffness and renal function. However, there are no prospective longitudinal studies in the literature.
  3. In dialysis patients, arterial stiffness as well as wave reflections, predict mortality. However, there are no data on patients with mild-to-moderate renal impairment available.
  4. Therefore, we designed a study to test the hypothesis that: a) measures of arterial stiffness and wave reflections predict the progression of renal impairment in patients with mild-to-moderate renal failure; and b) measures of arterial stiffness and wave reflections predict cardiovascular events in patients with mild-to-moderate renal failure
02

Conditions studied

  • Chronic Renal Failure
  • Arterial Stiffness
  • Arterial Wave Reflections

Keywords

  • chronic renal failure
  • arterial stiffness
  • arterial wave reflections
03

In context

Kidney Failure, Chronic

2,121 studies on the registry are indexed under Kidney Failure, Chronic; 264 are open to participants now.

This study's enrollment of 115 is close to the median of 120 across 441 observational studies indexed under Kidney Failure, Chronic.

Browse Kidney Failure, Chronic studies →

Lead sponsor

Klinikum Wels-Grieskirchen is the lead sponsor of 5 studies on the registry; none are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
19 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

patients with chronic renal failure

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • chronic renal failure patients (KDOQI III, IV) undergoing regular control visits at our nephrology department
  • > 19 years
  • written informed consent

Exclusion criteria

Exclusion Criteria:

  • atrial fibrillation
  • valvular heart disease
  • severely impaired systolic function
  • no informed consent
05

Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
115 participants (actual)
06

What researchers measure

Primary outcomes

  1. renal endpoint

    doubling serum creatinine, need for dialysis, renal transplantation

07

Study locations

1 site
  • Cardiology and Nephrology Department Klinikum Wels
    Wels, 4600, Austria
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Nov 4, 2010, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT00354588
Lead sponsor
Klinikum Wels-Grieskirchen
First posted
Jul 20, 2006
Start date
Jan 2006
Primary completion
Oct 2010
Completion
Oct 2010
Last update
Nov 4, 2010

Study contacts

Thomas Weber, MD
principal investigator · Cardiology Department, Klinikum Wels, Austria
Manfred Wallner, MD
principal investigator · Nephrology Department, Klinikum Wels, Austria
View the source record on ClinicalTrials.gov ↗

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This study is completed, as verified in Nov 2010. You cannot join it, but the record below documents what was studied.

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