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CompletedNCT00348543Updated Aug 5, 2011

Prophylactic Laser Treatment of Drusen Maculopathy

An interventional study of laser treatment in Age-related Macular Degeneration, sponsored by University Hospital, Linkoeping. Completed at 1 site in Sweden. Open to participants aged 55 Years and older. Per ClinicalTrials.gov, last updated 2011-08-05.

Sponsored by University Hospital, Linkoeping · Not applicable, Interventional, and Prevention

Phase
Not applicable
Study type
Interventional
Enrollment
150
Allocation
Randomized
Ages
55 Years and older
Sex
All
01

Study summary

To study the effect of mild laser treatment on the incidence of exudative complications in soft drusen maculopathy. We hypothesise that mild laser treatment causing a proliferation of the retinal pigment epithelium and enhancing the capacity of clearing drusen material from Bruch's membrane.

02

Conditions studied

  • Age-related Macular Degeneration

Keywords

  • age-related macula degeneration
  • prophylactic laser treatment
  • exudative complication
03

In context

Macular Degeneration

1,474 studies on the registry are indexed under Macular Degeneration; 206 are open to participants now.

This study's enrollment of 150 is above the median of 51 across 985 interventional studies indexed under Macular Degeneration.

Browse Macular Degeneration studies →

Lead sponsor

University Hospital, Linkoeping is the lead sponsor of 118 studies on the registry; 16 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
55 Years and older
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • > 55 years of age,
  • Soft drusen maculopathy,
  • VA 0.8-1.0

Exclusion criteria

Exclusion Criteria:

  • VA \<0.8,
  • Pigment clumps,
  • PED,
  • CNV,
  • Atrophy,
  • Haemorrhage,
  • Diabetes retinopathy,
  • Sign cataract,
  • Glaucoma
05

Study design

Phase
Not applicable
Primary purpose
Prevention
Allocation
Randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
150 participants

Interventions

  • Procedurelaser treatment
06

What researchers measure

Primary outcomes

  1. Change in visual acuity

Secondary outcomes

  1. incidence of exudative complications

07

Study locations

1 site
  • Dept of Ophthalmology, Linköping University
    Linköping, SE-581 85, Sweden
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Aug 5, 2011, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT00348543
Lead sponsor
University Hospital, Linkoeping
First posted
Jul 4, 2006
Start date
Dec 1999
Completion
Oct 2006
Last update
Aug 5, 2011

Study contacts

Christina I Frennesson, MD, PhD
principal investigator · Linkoeping University
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Oct 1999. You cannot join it, but the record below documents what was studied.

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