An observational study in Epilepsy, sponsored by King's College London. Completed at 1 site in United States. Open to participants aged 3 Years and older. Per ClinicalTrials.gov, last updated 2023-06-28.
Sponsored by King's College London · Observational
The purpose of this study is to find the genes that cause Rolandic epilepsy and its related traits.
Rolandic epilepsy (RE) is the most common type of childhood epilepsy-affecting more than 50,000 children in the United States-and has a complex genetic inheritance. The seizure prognosis is relatively benign, however, many children with RE also have problems with speech and language, reading, and motor coordination. Symptoms of the disorder overlap with more severe types of epilepsy.
The purpose of this study is to find the genes that influence RE and its related traits. Identifying genetic causes for the variants would improve diagnosis and allow for early intervention.
Researchers will enroll 1000 children with RE and 3000 controls for participation in the study. The scientists will request medical histories and (salivary) DNA samples from the participants. Participation can be completed by mail and telephone.
Results from this study should provide important information regarding diagnosis and prognosis of RE, may be useful in clinical management, and, eventually, may lead to a cure for this and other forms of epilepsy.
1,842 studies on the registry are indexed under Epilepsy; 423 are open to participants now.
This study's enrollment of 1,000 is above the median of 101 across 536 observational studies indexed under Epilepsy.
Browse Epilepsy studies →King's College London is the lead sponsor of 519 studies on the registry; 126 are open to participants now.
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Community Sample
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Exclusion:
Children with rolandic epilepsy
Individuals group matched to cases for ethnicity, sex and area of residence but lacking a primary brain disorder.
This study is completed, as verified in Aug 2011. You cannot join it, but the record below documents what was studied.
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