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TerminatedNCT00281333Updated Aug 30, 2011

The Influence of "Karate" on Bleeding in Hemophilic Patients.

An interventional study of "Karate" exercises and strengthening exercises in Hemophilia A, sponsored by Sheba Medical Center. Terminated. Open to male participants aged 11 Years to 19 Years. Per ClinicalTrials.gov, last updated 2011-08-30.

Sponsored by Sheba Medical Center · Not applicable, Interventional, and Prevention

Why this study was terminated
logistics
Phase
Not applicable
Study type
Interventional
Enrollment
12
Allocation
Non-randomized
Ages
11 Years to 19 Years
Sex
Male
01

Study summary

Hemophilia patients tend to lower their physical activity level due to the fear of increasing bleeding episodes. Although recent literature has shown that with routine muscle strengthening and physical activity, the frequency and duration of bleeds was reduced. Our study has built a routine of strength training exercises and karate training. The study is built in two stages, each stage being three months. The participants fill out a bleeding diary that includes information from the previous six months. It includes place of bleed, duration, pain level, spontaneous or traumatic bleed, factor replacement and joint limitation. Before the exercise, the participants are tested for muscle strength and endurance. The bleeding diary will be filled out following the first three months and the second phase as will the muscle strength and endurance. We are hoping to see a drastic reduction of bleeding episodes occurring especially from spontaneous bleeds.

Read the detailed description

none - Hemophilia patients tend to lower their physical activity level due to the fear of increasing bleeding episodes. Although recent literature has shown that with routine muscle strengthening and physical activity, the frequency and duration of bleeds was reduced. Our study has built a routine of strength training exercises and karate training. The study is built in two stages, each stage being three months. The participants fill out a bleeding diary that includes information from the previous six months. It includes place of bleed, duration, pain level, spontaneous or traumatic bleed, factor replacement and joint limitation. Before the exercise, the participants are tested for muscle strength and endurance. The bleeding diary will be filled out following the first three months and the second phase as will the muscle strength and endurance. We are hoping to see a drastic reduction of bleeding episodes occurring especially from spontaneous bleeds.

02

Conditions studied

  • Hemophilia A

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03

In context

Hemophilia A

885 studies on the registry are indexed under Hemophilia A; 139 are open to participants now.

This study's planned enrollment of 12 is below the median of 27 across 523 interventional studies indexed under Hemophilia A.

Browse Hemophilia A studies →

Lead sponsor

Sheba Medical Center is the lead sponsor of 677 studies on the registry; 63 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
11 Years to 19 Years
Sexes eligible
Male
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Severe Hemophilia.

Exclusion criteria

Exclusion Criteria:

  • No Inhibitors.
05

Study design

Phase
Not applicable
Primary purpose
Prevention
Allocation
Non-randomized
Intervention model
Single group
Masking
None (open label)
Enrollment
12 participants (estimated)

Interventions

  • Behavioral"Karate" exercises and strengthening exercises
06

Study locations

No study locations are listed for this record.

07

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Aug 30, 2011, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
08

Registry details

Key details

Study ID
NCT00281333
First posted
Jan 24, 2006
Completion
Oct 2006
Last update
Aug 30, 2011

Study contacts

Uri Martinowitz, M.D.
principal investigator · Sheba Medical Center

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is terminated, as verified in Aug 2011. You cannot join it, but the record below documents what was studied.

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