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CompletedNCT00185887Updated Mar 8, 2011

Nitroglycerin Versus Terbutaline for Intrapartum Fetal Resuscitation

An interventional study of Terbutaline in Fetal Distress, sponsored by Stanford University. Completed at 1 site in United States. Open to female participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2011-03-08.

Sponsored by Stanford University · Not applicable, Interventional, and Treatment

Phase
Not applicable
Study type
Interventional
Enrollment
110
Allocation
Randomized
Ages
18 Years and older
Sex
Female
01

Study summary

To compare nitroglycerin and terbutaline for intrapartum fetal heart rate resuscitation

02

Conditions studied

  • Fetal Distress

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03

In context

Fetal Distress

35 studies on the registry are indexed under Fetal Distress; 7 are open to participants now.

This study's enrollment of 110 is close to the median of 113 across 24 interventional studies indexed under Fetal Distress.

Browse Fetal Distress studies →

Lead sponsor

Stanford University is the lead sponsor of 2,117 studies on the registry; 425 are open to participants now.

Of its 259 completed or terminated interventional studies of FDA-regulated products, 197 (76%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
Female
Accepts healthy volunteers
No

Eligibility criteria

Inclusion Criteria::

  • nonreassuring fetal heart rate tracing Exclusion Criteria:- maternal cardiac disease, placental abruption, intrauterine growth restriction, prior cesarean section
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Single group
Masking
Quadruple (Participant, Care provider, Investigator, Outcomes assessor)
Enrollment
110 participants (actual)

Study arms

  • Active comparator
    Terbutaline

    Drug: Terbutaline

  • Active comparator
    Nitroglycerine

    Drug: Terbutaline

Interventions

  • DrugTerbutaline

    Terbutaline 250 micrograms intravenously for intrapartum fetal resuscitation. Nitroglycerine 400 micrograms intravenously for intrapartum fetal resuscitation.

06

What researchers measure

Primary outcomes

  1. resolution of abnormal fetal heart tracing

    Time frame: Administration of study medication to resolution of abnormal fetal heart tracing or operative delivery.

Secondary outcomes

  1. cesarean section rate

    Time frame: Data analysis

  2. operative vaginal delivery rate

    Time frame: Data analysis

  3. neonatal outcomes

    Time frame: time of delivery to time of discharge

07

Study locations

1 site
  • Stanford University School of Medicine
    Stanford, California 94305, United States
08

References and documents

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Mar 8, 2011, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT00185887
Lead sponsor
Stanford University
First posted
Sep 16, 2005
Start date
Oct 2003
Primary completion
Jul 2006
Completion
Oct 2007
Last update
Mar 8, 2011

Study contacts

Yasser Yehia El-Sayed
principal investigator · Stanford University
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Mar 2011. You cannot join it, but the record below documents what was studied.

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